Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope
Lukas Villiger(McGovern Institute for Brain Research), Gerald Schwank(University of Zurich), Kim Fabiano Marquart(University of Zurich), Lukas Schmidheini(University of Zurich), Nicolas Mathis(University of Zurich), Tanja Rothgangl(University of Zurich)
Cited by 21
Related Papers
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels
|Nature Biotechnology|2021|375
In vivo prime editing of a metabolic liver disease in mice
|Science Translational Medicine|2022|184
Predicting prime editing efficiency and product purity by deep learning
|Nature Biotechnology|2023|145