A flexible multiplexed immunosensor for point-of-care in situ wound monitoring
Yuji Gao(National University of Singapore), Dat T. Nguyen(National University of Singapore), Trifanny Yeo(National University of Singapore), Su Bin Lim(National University of Singapore), Wei Xian Tan(Singapore General Hospital), Leigh Madden(Nanyang Technological University), Lin Jin(National University of Singapore), Ji Yong Kenan Long(National University of Singapore), Fazila Aloweni(Singapore General Hospital), Yi Jia Angela Liew(Singapore General Hospital), Mandy Li Ling Tan(Nanyang Technological University), Shin Yuh Ang(Singapore General Hospital), Sivagame D O Maniya(Singapore General Hospital), Ibrahim Abdelwahab(National University of Singapore), Kian Ping Loh(National University of Singapore), Chia‐Hung Chen(City University of Hong Kong), David L. Becker(Agency for Science, Technology and Research), David I. Leavesley(Agency for Science, Technology and Research), John S. Ho(National University of Singapore), Chwee Teck Lim(National University of Singapore)
Cited by 264Open Access
Abstract
), and physicochemical parameters (temperature and pH) with a microfluidic wound exudate collector and flexible electronics for wireless, smartphone-based data readout. We demonstrate in situ multiplexed monitoring in a mouse wound model and also profile wound exudates from patients with venous leg ulcers. This technology may facilitate more timely and personalized wound management to improve chronic wound healing outcomes.
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