Design and linkage optimization of ursane-thalidomide-based PROTACs and identification of their targeted-degradation properties to MDM2 protein
Zhiwen Qi(Institute of Chemical Industry of Forest Products), Chengzhang Wang(Tianjin University of Technology), Tao Deng(Guangzhou University of Chinese Medicine), Sergey A. Popov(Novosibirsk Institute of Organic Chemistry), Elvira E. Shults(Novosibirsk Institute of Organic Chemistry), Hao Zhou(Institute of Chemical Industry of Forest Products), Jianmin Wang(Roswell Park Comprehensive Cancer Center), Yang Gu-liang(Central South University)
Cited by 37
Related Papers
Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity
|ChemMedChem|2019|193
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
|Journal of Medicinal Chemistry|2021|168
Design, Synthesis and Antibacterial Activity of Coumarin-1,2,3-triazole Hybrids Obtained from Natural Furocoumarin Peucedanin
|Molecules|2019|57
Efficient synthesis of the first betulonic acid–acetylene hybrids and their hepatoprotective and anti-inflammatory activity
|Bioorganic & Medicinal Chemistry|2009|50
Chromones and coumarins from Saposhnikovia divaricata (Turcz.) Schischk. Growing in Buryatia and Mongolia and their cytotoxicity
|Journal of Ethnopharmacology|2020|48