Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity
Thomas H. Pillow(Genesys (United States)), Peter S. Dragovich(Genesys (United States)), Shang‐Fan Yu(Genesys (United States)), Tracy Kleinheinz(Genesys (United States)), Brandon Latifi(Genesys (United States)), Isabel Figueroa(Merck & Co., Inc., Rahway, NJ, USA (United States)), Karen E. Gascoigne(Genesys (United States)), Jack Sadowsky(Genesys (United States)), Cong Wu(Second Military Medical University), Chun Sing Li(WuXi AppTec (China)), Rebecca K. Rowntree(Genesys (United States)), Donglu Zhang(Genesys (United States)), Pragya Adhikari(Genesys (United States)), Douglas D. Leipold(Genesys (United States)), Katherine R. Kozak(Genesys (United States)), Gauri Deshmukh(Genesys (United States)), Zijin Xu(WuXi AppTec (China)), Aimee O’Donohue(Genesys (United States)), Amrita V. Kamath(Genesys (United States)), Hongyan Zhang(Xintai People's Hospital), Xinxin Wang(Chinese PLA General Hospital), Jinhua Chen(WuXi AppTec (China)), Hui Yao(Wannan Medical College), Xiaoyu Zhu(WuXi AppTec (China)), Hao Zhou(Institute of Chemical Industry of Forest Products), Ruina Li(Genesys (United States)), Susan Kaufman(Genesys (United States)), Robert A. Blake(Exelixis (United States)), John Wai(WuXi AppTec (China)), Richard Zang(Genesys (United States)), Geoffrey Del Rosario(Genesys (United States)), Melinda M. Mulvihill(Genesys (United States))
Cited by 193
Related Papers
Validation of the ITS2 Region as a Novel DNA Barcode for Identifying Medicinal Plant Species
|PLoS ONE|2010|1.7k
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
|Nature Biotechnology|2008|1.4k
Use of ITS2 Region as the Universal DNA Barcode for Plants and Animals
|PLoS ONE|2010|1.2k
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
|Nature Biotechnology|2012|997