Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization

Wei Liu(Second People’s Hospital of Yibin), Weihua Cai(Rutgers, The State University of New Jersey), Jian Chen(Zhejiang Chinese Medical University), Fangyi Gong(Ningbo University Affiliated Hospital), Changjiang Gu(Nantong University), Jiaxing Wang(Northwest University), Linwei Li(Jiangsu Province Hospital), Zheng Zhou(Jiangsu Province Hospital), Fanqi Kong(Jacobson Holman (United States)), Dongdong Jiang(Nanjing Medical University), Jin Fan(Nanjing Medical University), Yuluo Rong(University of Science and Technology of China), Shujie Zhao(Jiangsu Province Hospital), Chengyue Ji(Jiangsu Province Hospital), Xuhui Ge(Second Military Medical University)
Journal of Neuroinflammation
February 4, 2020
10.1186/s12974-020-1726-7
Cited by 609

Related Papers

Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
|Nature|2019|982
Discovery of (10 <i>R</i> )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- <i>2H</i> -8,4-(metheno)pyrazolo[4,3- <i>h</i> ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations
|Journal of Medicinal Chemistry|2014|587
Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy
|Cell Death and Disease|2019|368
Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes
|Journal of Nanobiotechnology|2020|305
USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1
|Cell Death and Differentiation|2021|212