Assessing<scp>CYP</scp>2C19 Ontogeny in Neonates and Infants Using Physiologically Based Pharmacokinetic Models: Impact of Enzyme Maturation Versus Inhibition

Peng Duan(Cedars-Sinai Medical Center), Jian Wang(Foshan Hospital of TCM), Jeffrey W. Fisher(RTI International), Daniel González(University of North Carolina at Chapel Hill), Gilbert J. Burckart(Center for Drug Evaluation and Research), Lei Zhang(Institute of Hematology & Blood Diseases Hospital), Victor Crentsil(University of Pittsburgh), Fang Wu(Second Affiliated Hospital of Zhejiang University), Jason N. Moore(Center for Drug Evaluation and Research)
CPT Pharmacometrics & Systems Pharmacology
December 5, 2018
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