Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

Yuying Liu; Xiaoyu Liang; Wenqian Dong; Yi Fang; Jiadi Lv; Tianzhen Zhang; Roland Fiskesund; Jing Xie; Jinyan Liu; Xiaonan Yin; Xun Jin; Degao Chen; Ke Tang; Jingwei Ma; Huafeng Zhang; Jing Yu; Jun Yan; Huaping Liang; Siqi Mo; Feiran Cheng; Yabo Zhou; Haizeng Zhang; Jing Wang; Jingnan Li; Yang Chen; Bing Cui; Zhuo-Wei Hu; Xuetao Cao; F. Xiao‐Feng Qin; Bo Huang

doi:10.1016/j.ccell.2018.02.005

Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

Yuying Liu(Chinese Academy of Medical Sciences & Peking Union Medical College), Xiaoyu Liang(Chinese Academy of Medical Sciences & Peking Union Medical College), Wenqian Dong(Chinese Academy of Medical Sciences & Peking Union Medical College), Yi Fang(Chinese Academy of Medical Sciences & Peking Union Medical College), Jiadi Lv(Chinese Academy of Medical Sciences & Peking Union Medical College), Tianzhen Zhang(Chinese Academy of Medical Sciences & Peking Union Medical College), Roland Fiskesund(Chinese Academy of Medical Sciences & Peking Union Medical College), Jing Xie(Chinese Academy of Medical Sciences & Peking Union Medical College), Jinyan Liu(Chinese Academy of Medical Sciences & Peking Union Medical College), Xiaonan Yin(Chinese Academy of Medical Sciences & Peking Union Medical College), Xun Jin(Chinese Academy of Medical Sciences & Peking Union Medical College), Degao Chen(Chinese Academy of Medical Sciences & Peking Union Medical College), Ke Tang(Huazhong University of Science and Technology), Jingwei Ma(Huazhong University of Science and Technology), Huafeng Zhang(Chinese Academy of Medical Sciences & Peking Union Medical College), Jing Yu(Army Medical University), Jun Yan(Army Medical University), Huaping Liang(Army Medical University), Siqi Mo(Chinese Academy of Medical Sciences & Peking Union Medical College), Feiran Cheng(Chinese Academy of Medical Sciences & Peking Union Medical College), Yabo Zhou(Chinese Academy of Medical Sciences & Peking Union Medical College), Haizeng Zhang(Chinese Academy of Medical Sciences & Peking Union Medical College), Jing Wang(Chinese Academy of Medical Sciences & Peking Union Medical College), Jingnan Li(Chinese Academy of Medical Sciences & Peking Union Medical College), Yang Chen(Chinese Academy of Medical Sciences & Peking Union Medical College), Bing Cui(Chinese Academy of Medical Sciences & Peking Union Medical College), Zhuo-Wei Hu(Chinese Academy of Medical Sciences & Peking Union Medical College), Xuetao Cao(Chinese Academy of Medical Sciences & Peking Union Medical College), F. Xiao‐Feng Qin(Suzhou Institute of Systems Medicine), Bo Huang(Chinese Academy of Medical Sciences & Peking Union Medical College)

Cancer Cell

March 1, 2018

10.1016/j.ccell.2018.02.005

Cited by 519

Abstract

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