AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells

Nina Seiwert(University of Cagliari), Jörg Fahrer(University of Cagliari)

Cell Death and Disease

August 24, 2017

10.1038/cddis.2017.418

Cited by 45

Related Papers

DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP

|Nucleic Acids Research|2016|38

Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer

|Cancers|2021|16

Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery

|Archives of Toxicology|2023|14

Targeting PARP-1 and DNA Damage Response Defects in Colorectal Cancer Chemotherapy with Established and Novel PARP Inhibitors

|Cancers|2024|10

OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects

|Archives of Toxicology|2023|6