DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP

Maximilian Mimmler(Johannes Gutenberg University Mainz), Jörg Fahrer(University of Kaiserslautern)

Nucleic Acids Research

September 5, 2016

10.1093/nar/gkw791

Cited by 38

Related Papers

AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells

|Cell Death and Disease|2017|45

Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–A Workshop Report

|Planta Medica|2021|20

Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer

|Cancers|2021|16

Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery

|Archives of Toxicology|2023|14

Targeting PARP-1 and DNA Damage Response Defects in Colorectal Cancer Chemotherapy with Established and Novel PARP Inhibitors

|Cancers|2024|10