Abstract 1772: <i>PIK3CA</i> C2 domain deletions hyperactivate PI3K, generate oncogene dependence and are exquisitely sensitive to PI3Kα inhibitors

Sarah Croessmann(Vanderbilt University), Carlos L. Arteaga(The University of Texas Southwestern Medical Center), Rebecca Nagy(Guardant (United States)), Richard B. Lanman(C.T. de Wit Graduate School for Production Ecology and Resource Conservation), Jens Meiler(Leipzig University of Applied Sciences), Jonathan M. Irish(Vanderbilt University), Nalin Leelatian(Yale University), Lewis C. Cantley(Harvard University), Ingrid A. Mayer(Vanderbilt University), Justin M. Balko(Vanderbilt University Medical Center), Jie He(Foundation Medicine (United States)), Gregory Sliwoski(Vanderbilt University Medical Center), Vincent A. Miller(Universidad San Carlos), Jonathan H. Sheehan(Vanderbilt University)
Cancer Research
July 1, 2017
Cited by 0


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