Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Ingrid E. Christophersen; Michiel Rienstra; Carolina Roselli; Xiaoyan Yin; Bastiaan Geelhoed; John Barnard; Honghuang Lin; Dan E. Arking; Albert V. Smith; Christine M. Albert; Mark Chaffin; Nathan R. Tucker; Molong Li; Derek Klarin; Nathan A. Bihlmeyer; Siew‐Kee Low; Peter Weeke; Martina Müller‐Nurasyid; J. G. Smith; Jennifer A. Brody; Maartje N. Niemeijer; Marcus Dörr; Stella Trompet; Jennifer E. Huffman; Stefan Gustafsson; Claudia Schurmann; Marcus E. Kleber; Leo‐Pekka Lyytikäinen; Ilkka Seppälä; Rainer Malik; Andréa R. V. R. Horimoto; Marco Pérez; Juha Sinisalo; Stefanie Aeschbacher; Sébastien Thériault; Jie Yao; Farid Radmanesh; Stefan Weiß; Alexander Teumer; Seung Hoan Choi; Lu‐Chen Weng; Sebastian Clauß; Rajat Deo; Daniel J. Rader; Svati H. Shah; Albert Y. Sun; Jemma C. Hopewell; Stéphanie Debette; Ganesh Chauhan; Qiong Yang; Bradford B. Worrall; Guillaume Paré; Yoichiro Kamatani; Yanick Hagemeijer; Niek Verweij; Joylene E. Siland; Michiaki Kubo; Jonathan D. Smith; David R. Van Wagoner; Joshua C Bis; Siegfried Perz; Bruce M. Psaty; Paul M. Ridker; Jared W. Magnani; Tamara B. Harris; Lenore J. Launer; M. Benjamin Shoemaker; Sandosh Padmanabhan; Jeffrey Haessler; Traci M. Bartz; Mélanie Waldenberger; Peter Lichtner; Marina Arendt; José Eduardo Krieger; Mika Kähönen; Lorenz Risch; Alfredo José Mansur; Annette Peters; Blair H. Smith; Lars Lind; Stuart A. Scott; Yingchang Lu; Erwin B. Bottinger; Jussi Hernesniemi; Cecilia M. Lindgren; Jorge Wong; Jie Huang; Markku Eskola; Andrew P. Morris; Ian Ford; Alex P. Reiner; Graciela Delgado; Lin Y. Chen; Yii-Der Ida Chen; Roopinder K. Sandhu; Man Li; Eric Boerwinkle; Lewin Eisele; Lars Lannfelt; Natalia S. Rost; Christopher D. Anderson; Kent D. Taylor; Archie Campbell; Patrik K. E. Magnusson; David J. Porteous; Lynne J. Hocking; Efthymia Vlachopoulou; Nancy L. Pedersen; Kjell Nikus; Marju Orho‐Melander; Anders Hamsten; Jan Heeringa; Joshua C. Denny; Jennifer Kriebel; Dawood Darbar; Christopher Newton‐Cheh; Christian M. Shaffer; Peter W. Macfarlane; Stefanie Heilmann‐Heimbach; Peter Almgren; Paul L. Huang; Nona Sotoodehnia; Elsayed Z. Soliman; André G. Uitterlinden; Albert Hofman; Oscar H. Franco; Uwe Völker; Karl‐Heinz Jöckel; Moritz F. Sinner; Henry J. Lin; Xiuqing Guo; Martin Dichgans; Erik Ingelsson; Charles Kooperberg; Olle Melander; Ruth J. F. Loos; Jari Laurikka; David Conen; Jonathan Rosand; Pim van der Harst; Marja‐Liisa Lokki; Sekar Kathiresan; Alexandre C. Pereira; J. Wouter Jukema; Caroline Hayward; Jerome I. Rotter; Winfried März; Terho Lehtimäki; Bruno H. Stricker; Mina K. Chung; Stephan B. Felix; Vilmundur Guðnason; Álvaro Alonso; Dan M. Roden; Stefan Kääb; Daniel I. Chasman; Susan R. Heckbert; Emelia J. Benjamin; Toshihiro Tanaka; Kathryn L. Lunetta; Steven A. Lubitz; Patrick T. Ellinor

doi:10.1038/ng.3843

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Ingrid E. Christophersen(Broad Institute), Michiel Rienstra(University Medical Center Groningen), Carolina Roselli(Broad Institute), Xiaoyan Yin(Boston University), Bastiaan Geelhoed(University Medical Center Groningen), John Barnard(Cleveland Clinic), Honghuang Lin(Boston University), Dan E. Arking(Johns Hopkins University), Albert V. Smith(University of Iceland), Christine M. Albert(Brigham and Women's Hospital), Mark Chaffin(Broad Institute), Nathan R. Tucker(Broad Institute), Molong Li(Johns Hopkins University), Derek Klarin(Broad Institute), Nathan A. Bihlmeyer(Johns Hopkins University), Siew‐Kee Low(RIKEN Center for Integrative Medical Sciences), Peter Weeke(Copenhagen University Hospital), Martina Müller‐Nurasyid(Helmholtz Zentrum München), J. G. Smith(Broad Institute), Jennifer A. Brody(University of Washington), Maartje N. Niemeijer(Erasmus MC), Marcus Dörr(Universitätsmedizin Greifswald), Stella Trompet(Leiden University Medical Center), Jennifer E. Huffman(Institute of Genetics and Cancer), Stefan Gustafsson(Uppsala University), Claudia Schurmann(Icahn School of Medicine at Mount Sinai), Marcus E. Kleber(Heidelberg University), Leo‐Pekka Lyytikäinen(Tampere University), Ilkka Seppälä(Tampere University), Rainer Malik(Ludwig-Maximilians-Universität München), Andréa R. V. R. Horimoto(Universidade de São Paulo), Marco Pérez(Stanford University), Juha Sinisalo(Helsinki University Hospital), Stefanie Aeschbacher(University Hospital of Basel), Sébastien Thériault(Population Health Research Institute), Jie Yao(UCLA Medical Center), Farid Radmanesh(Broad Institute), Stefan Weiß(Universität Greifswald), Alexander Teumer(Universitätsmedizin Greifswald), Seung Hoan Choi(Broad Institute), Lu‐Chen Weng(Broad Institute), Sebastian Clauß(Massachusetts General Hospital), Rajat Deo(University of Pennsylvania), Daniel J. Rader(University of Pennsylvania), Svati H. Shah(Duke University), Albert Y. Sun(Duke University), Jemma C. Hopewell(University of Oxford), Stéphanie Debette(Boston University), Ganesh Chauhan(Université de Bordeaux), Qiong Yang(Boston University), Bradford B. Worrall(University of Virginia Health System), Guillaume Paré(Population Health Research Institute), Yoichiro Kamatani(RIKEN Center for Integrative Medical Sciences), Yanick Hagemeijer(University Medical Center Groningen), Niek Verweij(University Medical Center Groningen), Joylene E. Siland(University Medical Center Groningen), Michiaki Kubo(RIKEN Center for Integrative Medical Sciences), Jonathan D. Smith(Broad Institute), David R. Van Wagoner(Cleveland Clinic), Joshua C Bis(University of Washington), Siegfried Perz(Helmholtz Zentrum München), Bruce M. Psaty(Group Health Cooperative), Paul M. Ridker(Brigham and Women's Hospital), Jared W. Magnani(Boston University), Tamara B. Harris(National Institute on Aging), Lenore J. Launer(National Institute on Aging), M. Benjamin Shoemaker(Vanderbilt University Medical Center), Sandosh Padmanabhan(University of Glasgow), Jeffrey Haessler(University of Washington), Traci M. Bartz(University of Washington), Mélanie Waldenberger(Helmholtz Zentrum München), Peter Lichtner(Helmholtz Zentrum München), Marina Arendt(Institut für Medizinische Informatik, Biometrie und Epidemiologie), José Eduardo Krieger(Universidade de São Paulo), Mika Kähönen(Tampere University Hospital), Lorenz Risch(University of Bern), Alfredo José Mansur(Universidade de São Paulo), Annette Peters(Helmholtz Zentrum München), Blair H. Smith(University of Dundee), Lars Lind(Uppsala University), Stuart A. Scott(Icahn School of Medicine at Mount Sinai), Yingchang Lu(Icahn School of Medicine at Mount Sinai), Erwin B. Bottinger(Icahn School of Medicine at Mount Sinai), Jussi Hernesniemi(Tampere University Hospital), Cecilia M. Lindgren(Centre for Human Genetics), Jorge Wong(Hamilton Health Sciences), Jie Huang(Boston VA Research Institute), Markku Eskola(Tampere University Hospital), Andrew P. Morris(Centre for Human Genetics), Ian Ford(University of Glasgow), Alex P. Reiner(University of Washington), Graciela Delgado(Heidelberg University), Lin Y. Chen(University of Minnesota Medical Center), Yii-Der Ida Chen(UCLA Medical Center), Roopinder K. Sandhu(University of Alberta), Man Li(Johns Hopkins University), Eric Boerwinkle(Baylor College of Medicine), Lewin Eisele(Institut für Medizinische Informatik, Biometrie und Epidemiologie), Lars Lannfelt(Uppsala University), Natalia S. Rost(Broad Institute), Christopher D. Anderson(Broad Institute), Kent D. Taylor(UCLA Medical Center), Archie Campbell(Edinburgh Cancer Research), Patrik K. E. Magnusson(Karolinska Institutet), David J. Porteous(Edinburgh Cancer Research), Lynne J. Hocking(University of Aberdeen), Efthymia Vlachopoulou(University of Helsinki), Nancy L. Pedersen(Karolinska Institutet), Kjell Nikus(Tampere University Hospital), Marju Orho‐Melander(Lund University), Anders Hamsten(Karolinska Institutet), Jan Heeringa(Erasmus MC), Joshua C. Denny(Vanderbilt University Medical Center), Jennifer Kriebel(Helmholtz Zentrum München), Dawood Darbar(University of Illinois Chicago), Christopher Newton‐Cheh(Broad Institute), Christian M. Shaffer(Vanderbilt University Medical Center), Peter W. Macfarlane(University of Glasgow), Stefanie Heilmann‐Heimbach(University of Bonn), Peter Almgren(Lund University), Paul L. Huang(Massachusetts General Hospital), Nona Sotoodehnia(University of Washington), Elsayed Z. Soliman(Wake Forest University), André G. Uitterlinden(Erasmus MC), Albert Hofman(Erasmus MC), Oscar H. Franco(Erasmus MC), Uwe Völker(Universität Greifswald), Karl‐Heinz Jöckel(Institut für Medizinische Informatik, Biometrie und Epidemiologie), Moritz F. Sinner(German Centre for Cardiovascular Research), Henry J. Lin(Boston University), Xiuqing Guo(UCLA Medical Center), Martin Dichgans(German Center for Neurodegenerative Diseases), Erik Ingelsson(Uppsala University), Charles Kooperberg(University of Washington), Olle Melander(Lund University), Ruth J. F. Loos(Child Health and Development Institute), Jari Laurikka(Tampere University Hospital), David Conen(University Hospital of Basel), Jonathan Rosand(Broad Institute), Pim van der Harst(University Medical Center Groningen), Marja‐Liisa Lokki(University of Helsinki), Sekar Kathiresan(Broad Institute), Alexandre C. Pereira(Harvard University), J. Wouter Jukema(Leiden University Medical Center), Caroline Hayward(Institute of Genetics and Cancer), Jerome I. Rotter(UCLA Medical Center), Winfried März(Medical University of Graz), Terho Lehtimäki(Tampere University), Bruno H. Stricker(Dutch Health Care Inspectorate), Mina K. Chung(Cleveland Clinic), Stephan B. Felix(Universitätsmedizin Greifswald), Vilmundur Guðnason(University of Iceland), Álvaro Alonso(Emory University), Dan M. Roden(Vanderbilt University Medical Center), Stefan Kääb(German Centre for Cardiovascular Research), Daniel I. Chasman(Broad Institute), Susan R. Heckbert(Group Health Cooperative), Emelia J. Benjamin(Boston University), Toshihiro Tanaka(Tokyo Medical and Dental University), Kathryn L. Lunetta(Boston University), Steven A. Lubitz(Broad Institute), Patrick T. Ellinor(Broad Institute)

Nature Genetics

April 17, 2017

10.1038/ng.3843

Cited by 355Open Access

Full Text

Abstract

Related Papers

No related papers found

Powered by citation graph analysis