Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
European Alzheimer's Disease Initiative (EADI)(Inserm), Jean‐Charles Lambert(Inserm), Genetic and Environmental Risk in Alzheimer's Disease (GERAD)(Cardiff University), Carla A. Ibrahim‐Verbaas(Erasmus MC), Denise Harold(Cardiff University), Adam C. Naj(Université de Lille), Rebecca Sims(Boston University), Céline Bellenguez(Boston University), Gyungah Jun(Boston University), Anita L. DeStefano(Boston University), Joshua C Bis(University of Washington), Gary W. Beecham(University of Miami), Benjamin Grenier‐Boley(Inserm), Giancarlo Russo(University of Zurich), Tricia A. Thornton‐Wells(University of Iceland), Nicola Jones(Institut Pasteur de Lille), Albert V. Smith(University of Iceland), Vincent Chouraki(Inserm), Charlene Thomas(Cardiff University), M. Arfan Ikram(Boston University), Diana Zélénika(Fondation Jean Dausset-CEPH), Badri N. Vardarajan(Boston University), Yoichiro Kamatani(Fondation Jean Dausset-CEPH), Chiao‐Feng Lin(Medical University of Graz), Amy Gerrish(University of Miami), Helena Schmidt(Medical University of Graz), Brian W. Kunkle(University of Miami), Melanie Dunstan(Cardiff University), Agustı́n Ruiz(Boston University), Marie‐Thérèse Bihoreau(Columbia University), Seung‐Hoan Choi(Boston University), Christiane Reitz(Columbia University), Florence Pasquier(University of Bonn), Paul Hollingworth(Université Paris Cité), Alfredo Ramı́rez(University of Bonn), Olivier Hanon(Université Paris Cité), Annette L. Fitzpatrick(Inserm), Joseph D. Buxbaum(University of Washington), Dominique Campion(Boston University), Paul K. Crane(University of Washington), Clinton T. Baldwin(Boston University), Tim Becker(University of Bonn), Vilmundur Guðnason(Queen's University Belfast), Carlos Cruchaga(Washington University in St. Louis), David Craig(Queen's University Belfast), Najaf Amin(University of Pittsburgh), Claudine Berr(Brigham and Women's Hospital), Oscar L Lopez(University of Pittsburgh), Philip L. De Jager(Broad Institute), Vincent Deramecourt(Rush University Medical Center), Janet Johnston(Queen's University Belfast), Denis A. Evans(Rush University Medical Center), Simon Lovestone(King's College London), Luc Letenneur(Inserm), Francisco Jesús Morón(Icelandic Heart Association), David C. Rubinsztein(University of Cambridge), Gudny Eiriksdottir(Washington University in St. Louis), Kristel Sleegers(University of Antwerp), Alison Goate(Translational Genomics Research Institute), Nathalie Fiévet(Inserm), Matthew J. Huentelman(Translational Genomics Research Institute), Michael Gill(University of Pittsburgh), Kristelle Brown(University of Nottingham), M. Ilyas Kamboh(Inserm), Lina Keller(Queen's University Belfast), Pascale Barberger‐Gateau(Inserm), Bernadette McGuinness(Queen's University Belfast), Eric B. Larson(Group Health Cooperative), Robert C. Green(Brigham and Women's Hospital), Amanda Myers(Queen's University Belfast), Carole Dufouil(Inserm), Stephen Todd(Queen's University Belfast), David Wallon(Inserm), Seth Love(Frenchay Hospital), Ekaterina Rogaeva(University of Toronto), John Gallacher(Universitat Autònoma de Barcelona), Peter St George‐Hyslop(Universitat Autònoma de Barcelona), Jordi Clarimón(Universitat Autònoma de Barcelona), Alberto Lleó(Universitat Autònoma de Barcelona), Anthony Bayer(Rush University Medical Center), Debby W. Tsuang(Aristotle University of Thessaloniki), Lei Yu(Rush University Medical Center), Magda Tsolaki(Aristotle University of Thessaloniki), Paola Bossù(King's College London), Gianfranco Spalletta(MRC Prion Unit), Petroula Proitsi(King's College London), John Collinge(Hospital Universitario de Gran Canaria Doctor Negrín), Sandro Sorbi(UK Dementia Research Institute), Florentino Sánchez-García(Hospital Universitario de Gran Canaria Doctor Negrín), Nick C. Fox(Hospital Universitario de Gran Canaria Doctor Negrín), John Hardy(Oasi Maria SS), María Cándida Déniz Naranjo(University of Oxford), Paolo Bosco(University of Cambridge), Robert Clarke(University of Milan), Carol Brayne(University of Pisa), Daniela Galimberti(University of Milan), Michelangelo Mancuso(University of Pisa), Fiona E. Matthews(University of Perugia), Susanne Moebus(University of Cagliari), Patrizia Mecocci(University of Bonn), Maria Del Zompo(Goethe University Frankfurt), Wolfgang Maier(University of Bonn), Harald Hampel(Goethe University Frankfurt), Alberto Pilotto(Casa Sollievo della Sofferenza), María J. Bullido(University of Parma), Francesco Panza(University of Florence), Paolo Caffarra(University of Parma), Benedetta Nacmias(University of Florence), John R. Gilbert(Uppsala University), Manuel Mayhaus(Children's Hospital of Philadelphia), Lars Lannfelt(Uppsala University), Håkon Håkonarson(Children's Hospital of Philadelphia), Sabrina Pichler(Uppsala University), Minerva M. Carrasquillo(University of Washington), Martin Ingelsson(Uppsala University), Duane Beekly(University of Washington), Victoria Álvarez(Hospital Universitario Central de Asturias), Fanggeng Zou(Jacksonville College), Otto Valladares(Hospital Universitario Central de Asturias), Steven G. Younkin(University of Miami), Eliécer Coto(Hospital Universitario Central de Asturias), Kara L. Hamilton‐Nelson(University of Miami), Wei Gu(Universidad de Navarra), Cristina Razquín(Universidad de Cantabria), Pau Pástor(Instituto de Salud Carlos III), Ignacio Mateo(Universidad de Cantabria), Michael J. Owen(University of Iceland), Kelley M. Faber(Universidad de Cantabria), Pálmi V. Jónsson(Reykjavík University), Onofre Combarros(Universidad de Cantabria), Michael O‘Donovan(University of Eastern Finland), Laura B. Cantwell(Harvard University), Hilkka Soininen(University of Eastern Finland), Deborah Blacker(Harvard University), Simon Mead(Rush University Medical Center), Thomas H. Mosley(University of Washington), David Bennett(Rush University Medical Center), Tamara B. Harris(University of Washington), Laura Fratiglioni(Karolinska University Hospital), Clive Holmes(Queen's University Belfast), Renée F.A.G. de Bruijn(University of Washington), Peter Passmore(Queen's University Belfast), Thomas J. Montine(Cedars-Sinai Medical Center), Karolien Bettens(Centre National de la Recherche Scientifique), Jerome I. Rotter(Cedars-Sinai Medical Center), Alexis Brice(Centre National de la Recherche Scientifique), Kevin Morgan(University of Nottingham), Tatiana Foroud(Inserm), Walter A. Kukull(King's College London), Didier Hannequin(Inserm), John Powell(Inserm), Michael A. Nalls(Boston University), Karen Ritchie(Brigham Young University), Kathryn L. Lunetta(Boston University), John S.K. Kauwe(Brigham Young University), Eric Boerwinkle(Baylor College of Medicine), Matthias Riemenschneider(University of Eastern Finland), Merçé Boada(University of Miami), Mikko Hiltunen(University of Eastern Finland), Eden R. Martin(University of Miami), Reinhold Schmidt(Medical University of Graz), Dan Rujescu(Inserm), Li‐San Wang(Columbia University), Jean‐François Dartigues(Inserm), Richard Mayeux(Netherlands Consortium for Healthy Ageing), Christophe Tzourio(University of Bonn), Albert Hofman(Rush University Medical Center), Markus M. Nöthen(Group Health Cooperative), Caroline Graff(Rush University Medical Center), Bruce M. Psaty(Group Health Cooperative), Lesley Jones(Cardiff University), Jonathan L. Haines(Vanderbilt University), Peter Holmans(University of Miami), Mark Lathrop(Fondation Jean Dausset-CEPH), Margaret A. Pericak‐Vance(Boston University), Lenore J. Launer(Centre for Medical Systems Biology), Lindsay A. Farrer(Boston University), Cornelia M. van Duijn(Erasmus MC), Christine Van Broeckhoven(Boston University), Valentina Moskvina(Cardiff University), Sudha Seshadri(Boston University), Julie Williams(Centre Hospitalier Universitaire de Lille), Gerard D. Schellenberg(University of Pennsylvania), Philippe Amouyel(Inserm)
Cited by 4,645Open Access