Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

Veit Rothhammer(Brigham and Women's Hospital), Iván Mascanfroni(Brigham and Women's Hospital), Lukas Bunse(Brigham and Women's Hospital), Maisa C. Takenaka(Brigham and Women's Hospital), Jessica E. Kenison(Brigham and Women's Hospital), Lior Mayo(Brigham and Women's Hospital), Chun‐Cheih Chao(Brigham and Women's Hospital), Bonny Patel(Brigham and Women's Hospital), Raymond Yan(Brigham and Women's Hospital), Manon Blain(Montreal Neurological Institute and Hospital), Jorge I. Alvarez(University of Pennsylvania), Hania Kébir(Université de Montréal), Niroshana Anandasabapathy(Brigham and Women's Hospital), Guillermo Izquierdo(Universidad de Sevilla), Steffen Jung(Weizmann Institute of Science), Nikolaus D. Obholzer(Broad Institute), Nathalie Pochet(Broad Institute), Clary B. Clish(Broad Institute), Marco Prinz(University of Freiburg), Alexandre Prat(Université de Montréal), Jack P. Antel(Montreal Neurological Institute and Hospital), Francisco J. Quintana(Brigham and Women's Hospital)
Nature Medicine
May 9, 2016
10.1038/nm.4106
Cited by 1,511Open Access
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