Potent Cholesteryl Ester Transfer Protein Inhibitors of Reduced Lipophilicity: 1,1′-Spiro-Substituted Hexahydrofuroquinoline Derivatives
Thomas Trieselmann(Boehringer Ingelheim (Germany)), Herbert Nar(Boehringer Ingelheim (Germany)), Dieter Hamprecht, Klaus Fuchs(Boehringer Ingelheim (Germany)), Daniela Berta, Astrid Volz(Boehringer Ingelheim (Germany)), Paolo Cremonesi, Rüdiger Streicher(Boehringer Ingelheim (Germany)), Gerd Luippold(Boehringer Ingelheim (Germany)), Holger Wagner(Boehringer Ingelheim (Germany)), Michael Markert(Boehringer Ingelheim (Germany))
Cited by 27
Related Papers
Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5·5 and pH 9·0
|Journal of Molecular Biology|1991|487
Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors
|Journal of Medicinal Chemistry|2002|454
Biophysics in drug discovery: impact, challenges and opportunities
|Nature Reviews Drug Discovery|2016|383