ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies

Jo Ishizawa(The University of Texas MD Anderson Cancer Center), Michael Andreeff(The University of Texas MD Anderson Cancer Center), Vivian Ruvolo(Hormel (United States)), Marina Konopleva(Albert Einstein College of Medicine), Dos D. Sarbassov(Nazarbayev University), Hong Mu(Tianjin First Center Hospital), Robert Z. Orlowski(University of North Carolina at Chapel Hill), Yoko Tabe(Juntendo University), Peter P. Ruvolo(The University of Texas MD Anderson Cancer Center), Zhihong Zeng(The University of Texas MD Anderson Cancer Center), Hans C. Lee(The University of Texas MD Anderson Cancer Center), Gautam Borthakur(The University of Texas MD Anderson Cancer Center), Xuelin Huang(The University of Texas MD Anderson Cancer Center), Roberto N. Miranda(The University of Texas MD Anderson Cancer Center), Philip L. Lorenzi(City Of Hope National Medical Center), R. Eric Davis(The University of Texas MD Anderson Cancer Center), Sattva S. Neelapu(The University of Texas MD Anderson Cancer Center), Dhruv Chachad(The University of Texas MD Anderson Cancer Center), Timothy J. McDonnell(Health Service Executive), Hagop M. Kantarjian(The University of Texas MD Anderson Cancer Center), Zhiqiang Wang, Michael Wang(St. Joseph Health System), Kensuke Kojima(Kōchi University), Rodrigo Jácamo, Wencai Ma(The University of Texas MD Anderson Cancer Center), Joshua E. Allen(Chimerix (United States))
Science Signaling
February 16, 2016
Cited by 204


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