Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

David J. Roberts; Carmel Moore; Shelagh Joss; Sebastian S. Gerety; Andrew M. McIntosh; Gerome Breen; David Collier; Outi Kuismin; Tiina Paunio; Willem H. Ouwehand; Mitja Kurki; Daniel H. Geschwind; Lucy Crooks; Nelson B. Freimer; Peter Holmans; Robin Murray; Eve L. Coomber; Nick Craddock; Moira Blyth; Elliott Rees; Himanshu Chheda; Elena Prigmore; Peter McGuffin; George Kirov; Shaun Purcell; Tarjinder Singh; Jeremy F. McRae; Minna Männikkö; Jarmo Körkkö; Muhammad Ayub; Andrew McQuillin; David Curtis; Jouko Lönnqvist; Olli Pietiläinen; Douglas Blackwood; Jaana Suvisaari; Jukka S. Moilanen; Ruth Newbury‐Ecob; Mandy Johnstone; Marta Di Forti; Alison Foster; Trevor Cole; Mark J. Daly; John Danesh; Steve McCarroll; Conrad Iyegbe; Christina M. Hultman

doi:10.1038/nn.4267

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

David J. Roberts(NHS Blood and Transplant), Carmel Moore(University of Cambridge), Shelagh Joss(Oulu University Hospital), Sebastian S. Gerety(Wellcome Sanger Institute), Andrew M. McIntosh(Edinburgh Cancer Research), Gerome Breen(Institute for Neurodegenerative Disorders), David Collier(Queen Mary University of London), Outi Kuismin(King's College London), Tiina Paunio(King's College London), Willem H. Ouwehand(NHS Blood and Transplant), Mitja Kurki(Broad Institute), Daniel H. Geschwind(University of California, Los Angeles), Lucy Crooks(University of Helsinki), Nelson B. Freimer(University of California, Los Angeles), Peter Holmans(Cardiff University), Robin Murray(South London and Maudsley NHS Foundation Trust), Eve L. Coomber(Wellcome Sanger Institute), Nick Craddock(King's College London), Moira Blyth(Chapel Allerton Hospital), Elliott Rees(Cardiff University), Himanshu Chheda(University of Helsinki), Elena Prigmore(University of Cambridge), Peter McGuffin(King's College London), George Kirov(Cardiff University), Shaun Purcell(Columbia University Irving Medical Center), Tarjinder Singh(Wellcome Sanger Institute), Jeremy F. McRae(Royal Edinburgh Hospital), Minna Männikkö(Royal Edinburgh Hospital), Jarmo Körkkö(Oulu University Hospital), Muhammad Ayub(King's College London), Andrew McQuillin(University College London), David Curtis(University College London), Jouko Lönnqvist(Finnish Institute for Health and Welfare), Olli Pietiläinen(deCODE Genetics (Iceland)), Douglas Blackwood(Royal Edinburgh Hospital), Jaana Suvisaari, Jukka S. Moilanen(Oulu University Hospital), Ruth Newbury‐Ecob(University Hospitals Bristol NHS Foundation Trust), Mandy Johnstone(Oulu University Hospital), Marta Di Forti(South London and Maudsley NHS Foundation Trust), Alison Foster(Royal Edinburgh Hospital), Trevor Cole(Birmingham Women's Hospital), Mark J. Daly(Broad Institute), John Danesh(University of California, Los Angeles), Steve McCarroll(Broad Institute), Conrad Iyegbe(Broad Institute), Christina M. Hultman(Karolinska Institutet)

Nature Neuroscience

March 14, 2016

10.1038/nn.4267

Cited by 476

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