Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Swedish Schizophrenia Study; Tarjinder Singh; INTERVAL Study; DDD Study; Mitja Kurki; David Curtis; Shaun Purcell; Lucy Crooks; Jeremy F. McRae; Jaana Suvisaari; Himanshu Chheda; Douglas Blackwood; Gerome Breen; Olli Pietiläinen; Sebastian S. Gerety; Muhammad Ayub; Moira Blyth; Trevor Cole; David Collier; Eve L. Coomber; Nick Craddock; Mark J. Daly; John Danesh; Marta Di Forti; Alison Foster; Nelson B. Freimer; Daniel H. Geschwind; Mandy Johnstone; Shelagh Joss; George Kirov; Jarmo Körkkö; Outi Kuismin; Peter Holmans; Christina M. Hultman; Conrad Iyegbe; Jouko Lönnqvist; Minna Männikkö; Steve McCarroll; Peter McGuffin; Andrew M. McIntosh; Andrew McQuillin; Jukka S. Moilanen; Carmel Moore; Robin Murray; Ruth Newbury‐Ecob; Willem H. Ouwehand; Tiina Paunio; Elena Prigmore; Elliott Rees; David J. Roberts; Jennifer Sambrook; Pamela Sklar; David St Clair; Juha Veijola; James Walters; Hywel Williams; Patrick F. Sullivan; Matthew E. Hurles; Michael O‘Donovan; Aarno Palotie; Michael J. Owen; Jeffrey C. Barrett

doi:10.1038/nn.4267

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Swedish Schizophrenia Study(Wellcome Sanger Institute), Tarjinder Singh(Broad Institute), INTERVAL Study(University College London), DDD Study(Icahn School of Medicine at Mount Sinai), Mitja Kurki(Broad Institute), David Curtis(Wellcome Sanger Institute), Shaun Purcell(Finnish Institute for Health and Welfare), Lucy Crooks(University of Helsinki), Jeremy F. McRae(Royal Edinburgh Hospital), Jaana Suvisaari(King's College London), Himanshu Chheda(University of Helsinki), Douglas Blackwood(Royal Edinburgh Hospital), Gerome Breen(King's College London), Olli Pietiläinen(University of Helsinki), Sebastian S. Gerety(Wellcome Sanger Institute), Muhammad Ayub(King's College London), Moira Blyth(Chapel Allerton Hospital), Trevor Cole(Birmingham Women's Hospital), David Collier(Broad Institute), Eve L. Coomber(Wellcome Sanger Institute), Nick Craddock(King's College London), Mark J. Daly(Broad Institute), John Danesh(University of California, Los Angeles), Marta Di Forti(University of California, Los Angeles), Alison Foster(Royal Edinburgh Hospital), Nelson B. Freimer(University of California, Los Angeles), Daniel H. Geschwind(University of California, Los Angeles), Mandy Johnstone(Oulu University Hospital), Shelagh Joss(Oulu University Hospital), George Kirov(Cardiff University), Jarmo Körkkö(Oulu University Hospital), Outi Kuismin(King's College London), Peter Holmans(Finnish Institute for Health and Welfare), Christina M. Hultman(Karolinska Institutet), Conrad Iyegbe(Broad Institute), Jouko Lönnqvist(King's College London), Minna Männikkö(Royal Edinburgh Hospital), Steve McCarroll(Broad Institute), Peter McGuffin(King's College London), Andrew M. McIntosh(University of Cambridge), Andrew McQuillin(King's College London), Jukka S. Moilanen(Oulu University Hospital), Carmel Moore(University of Cambridge), Robin Murray(University of Helsinki), Ruth Newbury‐Ecob(University Hospitals Bristol NHS Foundation Trust), Willem H. Ouwehand(NHS Blood and Transplant), Tiina Paunio(University of Helsinki), Elena Prigmore(University of Cambridge), Elliott Rees(Cardiff University), David J. Roberts(NHS Blood and Transplant), Jennifer Sambrook(University of Cambridge), Pamela Sklar(Cardiff University), David St Clair(University of Aberdeen), Juha Veijola(Oulu University Hospital), James Walters(Wellcome Sanger Institute), Hywel Williams(Cardiff University), Patrick F. Sullivan(Broad Institute), Matthew E. Hurles(Wellcome Sanger Institute), Michael O‘Donovan(Wellcome Sanger Institute), Aarno Palotie(Broad Institute), Michael J. Owen(Wellcome Sanger Institute), Jeffrey C. Barrett(Wellcome Sanger Institute)

Nature Neuroscience

March 14, 2016

10.1038/nn.4267

Cited by 476Open Access

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