SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange.
Stephen Felder, Joseph Schlessinger(Yale University), Jesús M. Ureña(Universitat de Barcelona), Morris F. White(Joslin Diabetes Center), Min Zhou(East China University of Science and Technology), Manas K. Chaudhuri, Steven E. Shoelson(Joslin Diabetes Center), A. Ullrich(University of Washington), Patrick J Hu(University of Michigan)
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