Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou(Beth Israel Deaconess Medical Center), Yimin Yu(Massachusetts Institute of Technology), William J. Israelsen(Massachusetts Institute of Technology), Jian‐kang Jiang(National Institutes of Health), Matthew B. Boxer(National Institutes of Health), Bum Soo Hong(Structural Genomics Consortium), W. Tempel(Structural Genomics Consortium), Svetoslav Dimov(University of Toronto), Min Shen(National Institutes of Health), Abhishek Jha(Massachusetts Institute of Technology), Hua Yang(Agios Pharmaceuticals (United States)), Katherine Mattaini(Massachusetts Institute of Technology), Christian M. Metallo(University of California, San Diego), Brian P. Fiske(Massachusetts Institute of Technology), Kevin D. Courtney(Center for Systems Biology), Scott Malstrom(Massachusetts Institute of Technology), Tahsin Khan(Massachusetts Institute of Technology), Charles Kung(Agios Pharmaceuticals (United States)), Amanda P. Skoumbourdis(National Institutes of Health), Henrike Veith(National Center for Advancing Translational Sciences), Noel Southall(National Institutes of Health), Martin J. Walsh(National Institutes of Health), Kyle R. Brimacombe(National Institutes of Health), William Leister(National Center for Advancing Translational Sciences), Sophia Y. Lunt(Massachusetts Institute of Technology), Zachary Johnson(Massachusetts Institute of Technology), Katharine Yen(Agios Pharmaceuticals (United States)), Kaiko Kunii(Agios Pharmaceuticals (United States)), Shawn M. Davidson(Massachusetts Institute of Technology), Heather R. Christofk(Beth Israel Deaconess Medical Center), Christopher P. Austin(National Institutes of Health), James Inglese(National Institutes of Health), Marian H. Harris(Boston Children's Hospital), John M. Asara(Harvard University), Gregory Stephanopoulos(Massachusetts Institute of Technology), Francesco G. Salituro(Agios Pharmaceuticals (United States)), Shengfang Jin(Agios Pharmaceuticals (United States)), Lenny Dang(Agios Pharmaceuticals (United States)), Douglas S. Auld(National Institutes of Health), Hee‐Won Park(Structural Genomics Consortium), Lewis C. Cantley(Beth Israel Deaconess Medical Center), Craig J. Thomas(National Institutes of Health), Matthew G. Vander Heiden(Massachusetts Institute of Technology)
Nature Chemical Biology
August 26, 2012
Cited by 822Open Access
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