Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
Chris H. Polman(University of Amsterdam), Stephen C. Reingold(Clinical Research Associates), Brenda Banwell(University of Toronto), M. Clanet, Jeffrey A. Cohen(Cleveland Clinic), Massimo Filippi(San Raffaele University of Rome), Kazuo Fujihara(Tohoku University), Eva Havrdová(Charles University), Michael Hutchinson(University College Dublin), Ludwig Kappos(University of Basel), Fred Lublin(Icahn School of Medicine at Mount Sinai), Xavier Montalbán(Vall d'Hebron Hospital Universitari), Paul O’Connor(St. Michael's Hospital), Magnhild Sandberg‐Wollheim(Lund University), Alan J. Thompson(UCL Australia), Emmanuelle Waubant(University of California, San Francisco), Brian G. Weinshenker(Mayo Clinic), Jerry S. Wolinsky(The University of Texas Health Science Center at Houston)
Cited by 9,811Open Access
Abstract
New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use.
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