SAbDab: the structural antibody database
James B. Dunbar, Konrad Krawczyk(University of Oxford), Jinwoo Leem(UCB Pharma (United Kingdom)), Terry Baker(UCB Pharma (United Kingdom)), Angelika Fuchs(UCB Pharma (United Kingdom)), Guy Georges(Roche (United Kingdom)), Jiye Shi(UCB Pharma (United Kingdom)), Charlotte M. Deane(UCB Pharma (United Kingdom))
Cited by 713Open Access
Abstract
Structural antibody database (SAbDab; http://opig.stats.ox.ac.uk/webapps/sabdab) is an online resource containing all the publicly available antibody structures annotated and presented in a consistent fashion. The data are annotated with several properties including experimental information, gene details, correct heavy and light chain pairings, antigen details and, where available, antibody-antigen binding affinity. The user can select structures, according to these attributes as well as structural properties such as complementarity determining region loop conformation and variable domain orientation. Individual structures, datasets and the complete database can be downloaded.
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