A Physical Map of 30,000 Human Genes

Panos Deloukas(Wellcome Sanger Institute), Gregory D. Schuler(Wellcome Sanger Institute), Gàbor Gyapay(Wellcome Sanger Institute), Edward Beasley(Wellcome Sanger Institute), Carol Soderlund(Wellcome Sanger Institute), Patricia Rodriguez‐Tomé(Wellcome Sanger Institute), Lester Hui(Wellcome Sanger Institute), Tara C. Matise(Wellcome Sanger Institute), Kathleen B. McKusick(Wellcome Sanger Institute), J. Beckmann(Wellcome Sanger Institute), S Bentolila(Wellcome Sanger Institute), Marie Thérèse Bihoreau(Wellcome Sanger Institute), B. B. Birren(Wellcome Sanger Institute), J.M.W. Browne(Wellcome Sanger Institute), Adam P. Butler(Wellcome Sanger Institute), Andrew B. Castle(Wellcome Sanger Institute), Nuchanard Chiannilkulchai(Wellcome Sanger Institute), Christopher Clee(Wellcome Sanger Institute), Philip J. Day(Wellcome Sanger Institute), Anindya Dehejia(Wellcome Sanger Institute), Thomas Dibling(Wellcome Sanger Institute), Nathalie Drouot(Wellcome Sanger Institute), Simone Duprat(Wellcome Sanger Institute), Cécile Fizames(Wellcome Sanger Institute), Samuel E. Fox(Wellcome Sanger Institute), Stephen Gelling(Wellcome Sanger Institute), L. Green(Wellcome Sanger Institute), Pat Heslop Harrison(Wellcome Sanger Institute), Richard J. Hocking(Wellcome Sanger Institute), Eric Holloway(Wellcome Sanger Institute), Sarah Hunt(Wellcome Sanger Institute), S. Keil(Wellcome Sanger Institute), Philip Lijnzaad(Wellcome Sanger Institute), Christine Louis-Dit-Sully(Wellcome Sanger Institute), Junli Ma(Wellcome Sanger Institute), A. Mendis(Wellcome Sanger Institute), Jeffery L. Miller(Wellcome Sanger Institute), J Morissette(Wellcome Sanger Institute), Delphine Muselet(Wellcome Sanger Institute), H. C. Nusbaum(Wellcome Sanger Institute), Allison M. Peck(Wellcome Sanger Institute), Steve Rozen(Wellcome Sanger Institute), D Simon(Wellcome Sanger Institute), Donna K. Slonim(Wellcome Sanger Institute), Richard C. Staples(Wellcome Sanger Institute), Lincoln Stein(Wellcome Sanger Institute), Elizabeth A. Stewart(Wellcome Sanger Institute), Marc A. Suchard(Wellcome Sanger Institute), T. Thangarajah(Wellcome Sanger Institute), Nathalie Vega-Czarny(Wellcome Sanger Institute), Caleb Webber(Wellcome Sanger Institute), Xiaolin Wu(Wellcome Sanger Institute), James R. Hudson(Wellcome Sanger Institute), Charles Auffray(Wellcome Sanger Institute), Nobuhiko Nomura(Wellcome Sanger Institute), James M. Sikela(Wellcome Sanger Institute), Mihael H. Polymeropoulos(Wellcome Sanger Institute), M R James(Wellcome Sanger Institute), Eric S. Lander(Wellcome Sanger Institute), Thomas J. Hudson(Wellcome Sanger Institute), R Myers(Wellcome Sanger Institute), David R. Cox(Wellcome Sanger Institute), J. Weissenbach(Wellcome Sanger Institute), Mark S. Boguski(Wellcome Sanger Institute), D. R. Bentley(Wellcome Sanger Institute)
Science
October 23, 1998
10.1126/science.282.5389.744
Cited by 714

Abstract

A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The new gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross-referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.

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