DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

Xuesong Liu; Hua Zou; Clive A. Slaughter; Xiaodong Wang

doi:10.1016/s0092-8674(00)80197-x

DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

Xuesong Liu(Emory University), Hua Zou(The University of Texas Southwestern Medical Center), Clive A. Slaughter(Howard Hughes Medical Institute), Xiaodong Wang(The University of Texas Southwestern Medical Center)

Cell

April 1, 1997

10.1016/s0092-8674(00)80197-x

Cited by 1,841Open Access

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Abstract

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al.|Science|1997|4.9k

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

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Human ICE/CED-3 Protease Nomenclature

Emad S. Alnemri, David J. Livingston, Donald W. Nicholson et al.|Cell|1996|2.4k

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

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DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

Abstract

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