Characterization of the Ectodomain Shedding of the β-Site Amyloid Precursor Protein-cleaving Enzyme 1 (BACE1)
Ishrut Hussain(GlaxoSmithKline (United Kingdom)), Colin Dingwall(GlaxoSmithKline (United Kingdom)), Julie A. Hawkins(Charles River Laboratories (United Kingdom)), David Riddell(Eli Lilly (United States)), Aarti Shikotra(University of Leicester), Andrew Faller(GlaxoSmithKline (United Kingdom))
Cited by 59
Related Papers
ApoE Promotes the Proteolytic Degradation of Aβ
|Neuron|2008|869
Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor
|Journal of Medicinal Chemistry|2012|460
Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels
|Journal of Neuroscience|2008|351
Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts
|Current Biology|2001|302
The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease
|Molecular and Cellular Neuroscience|2007|248