Specific Calpain Inhibition by Calpastatin Prevents Tauopathy and Neurodegeneration and Restores Normal Lifespan in Tau P301L Mice
Mala V. Rao(Dementia UK), Ralph A. Nixon(Nathan Kline Institute for Psychiatric Research)
Cited by 98
Related Papers
Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
|Journal of Neuroscience|2008|1.1k
Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome
|American Journal Of Pathology|2000|847
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
|Nature Neuroscience|2022|606
Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
|Journal of Neuroscience|2011|466
Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases
|Nature Reviews Molecular Cell Biology|2024|275