CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND

Solomon H. Snyder(National Institute of Mental Health), M H Zweig(National Institute of Mental Health), Julius Axelrod(National Institute of Mental Health), Josef E. Fischer(National Institute of Mental Health)
Proceedings of the National Academy of Sciences
February 1, 1965
Cited by 172Open Access
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Abstract

In this article, Axelrod and several members of his laboratory reported their findings on circadian rhythms and the results of a series of experiments on the pineal glands of rats. The researchers found that the circadian rhythm was synchronized by exposure to light, but otherwise operated independent of it. However, exposure to constant light, or blinding the rats altogether, significantly altered their circadian rhythms.


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