Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

 Bryan J Mowry(The University of Queensland), Sang Lee(Broad Institute),  Peter M Visscher (Broad Institute), Enda M. Byrne(The University of Queensland), Naomi R. Wray(Broad Institute),  Shaun M Purcell(Broad Institute),  Soumya Raychaudhuri (Broad Institute), Benjamin M. Neale(Broad Institute), Stephan Ripke(Broad Institute), Mark J. Daly(Broad Institute), Verneri Anttila(Harvard University), Sarah E. Bergen(Broad Institute),  Shaun M Purcell(Broad Institute), Lizzy Rossin(Broad Institute), Benjamin M. Neale(Broad Institute), Mark J. Daly(Broad Institute), Stephan Ripke(Broad Institute), Colm Ó'Dúshláine(Broad Institute),  Soumya Raychaudhuri(Broad Institute), Edward M. Scolnick(Broad Institute),  Jordan W Smoller(Broad Institute), Steven A. McCarroll(Broad Institute), Jennifer L. Moran(Broad Institute),  Roy H Perlis(Broad Institute), Kimberly Chambert(Broad Institute), Stephen V Faraone(SUNY Upstate Medical University), Stephen V Faraone(GlaxoSmithKline (United Kingdom)), Shaun Purcell(Broad Institute), Douglas M. Ruderfer(University College London), Pamela Sklar(Icahn School of Medicine at Mount Sinai), Roy H Perlis(Broad Institute),  Jordan W Smoller(Broad Institute),  Phil H Lee (Massachusetts General Hospital), Sarah E. Bergen(Broad Institute), Bryan J Mowry(The University of Queensland),  Christine Fraser(Centre National de la Recherche Scientifique), Peter Holmans(Max Planck Society),  Stanley Zammit(Harvard University Press), Katherine Gordon‐Smith(Max Planck Society), Nicholas Craddock(University of Iowa), Lyudmila Georgieva(Cardiff Council),  George K Kirov(Scripps Health), Detelina Grozeva(University of Michigan), Ian D. Jones(Cardiff Council), Marian L. Hamshere(King's College London),  Valentina Moskvina(Heidelberg University),  Ivan Nikolov(University of Groningen),  Nigel Williams(Trinity College Dublin), Michael O‘Donovan(Cardiff Council), Michael J. Owen(Radboud University Nijmegen), Anita Thapar(University of California, Irvine),  Christine Fraser(Cardiff Council),  Stanley Zammit(University of California, San Francisco), Nicholas Craddock(The University of Queensland), Lyudmila Georgieva(Cardiff Council),  George K Kirov(Utrecht University), Ian D. Jones(University of California, Los Angeles),  Nigel Williams(Universitat Autònoma de Barcelona),  Ivan Nikolov(Johns Hopkins University), Michael O‘Donovan(Broad Institute), Michael J. Owen(Cardiff Council), Anita Thapar(University of Bonn), Michael E. Goddard(Washington University in St. Louis), Michael E. Goddard(King's College London), John S Witte(University of California, San Francisco), Devin Absher(University of Utah), Richard M. Myers(HudsonAlpha Institute for Biotechnology), Ingrid Agartz(University of Oslo), Srdjan Djurovic(University of Iowa), Morten Mattingsdal(Translational Genomics Research Institute), Ole A. Andreassen(Oslo University Hospital), Ingrid Melle(Oslo University Hospital), Ingrid Agartz(University of Miami), Robert C. Thompson(Queen Mary University of London), Stanley J. Watson(Max Planck Society), Huda Akil(University of Michigan), Fan Meng(University of North Carolina at Chapel Hill), Farooq Amin(University of Dundee), Ole A. Andreassen(Oslo University Hospital), Ingrid Melle(Oslo University Hospital), Robert Krasucki(University of Oslo), Adebayo Anjorin(Trinity College Dublin), Khalid Choudhury(Harvard University Press), Jacob Lawrence(University of Chicago), Hugh Gurling(University of London), Jonathan Pimm(Goethe University Frankfurt), Nicholas Bass(National University of Singapore), Radhika Kandaswamy(Indiana University Bloomington), Andrew McQuillin(University College London), Vinay Puri(University College London), Elaine Kenny(Trinity College Dublin), Aiden Corvin(Georgetown University), Paul Cormican(King's College London), Derek W. Morris(Trinity College Dublin), Richard Anney(Trinity College Dublin), Emma M. Quinn(Oregon Health & Science University), Gary Donohoe(Trinity College Dublin), Michael Gill(Trinity College Dublin), Louise Gallagher(Radboud University Nijmegen), Dan E. Arking(Johns Hopkins University), Aravinda Chakravarti(Johns Hopkins University), Peter McGuffin(University of California, Los Angeles), David Collier(Goethe University Frankfurt),  Gerome Breen(King's College London), Ian Craig(King's College London), Anne Farmer(King's College London), Philip Asherson(King's College London), Jonna Kuntsi(King's College London), Cathryn M. Lewis(King's College London), Maria Helena Pinto de Azevedo(University of California, Los Angeles), Guiomar Oliveira(Hospitais da Universidade de Coimbra), Urban Ösby(Trinity College Dublin), Martin Schalling(QIMR Berghofer Medical Research Institute), Louise Frisén(Karolinska Institutet), Lena Backlund(Karolinska Institutet), Elliot S. Gershon(University of California San Diego), Judith A. Badner(University of Chicago), Anthony Bailey(University of Bonn), Tobias Banaschewski(Heidelberg University), Jack D. Barchas(Cornell University), Michael R. Barnes(GlaxoSmithKline (United Kingdom)), Thomas B. Barrett(Portland VA Medical Center), Agatino Battaglia(Vanderbilt University), Michael Bauer(University Hospital Carl Gustav Carus), Mónica Bayés(Centro Nacional de Análisis Genómico),  Stéphane Jamain (Inserm), Frank Bellivier(Inserm), Bruno Étain(University of Copenhagen), Marion Leboyer(Inserm), Frank Bellivier(Inserm), Frank Bellivier(Inserm),  Stéphane Jamain (Inserm), Frank Bellivier(University of Bonn), Bruno Étain(The University of Sydney),  Marion Leboyer(Howard University), Mikael Landén(University of Bonn), Patrik K. E. Magnusson(Karolinska Institutet), Paul Lichtenstein(Max Planck Society), Sarah E. Bergen(Broad Institute), Christina M. Hultman(Karolinska Institutet), Anna K. Kähler(Karolinska Institutet), Niklas Långström(University of Michigan), Josephine Elia(University of Copenhagen), Wade H. Berrettini(Max Planck Society), Falk W. Lohoff(University of Pennsylvania), Catalina Betancur(Centre National de la Recherche Scientifique), Catalina Betancur(Centre National de la Recherche Scientifique), Catalina Betancur(Centre National de la Recherche Scientifique), Marcus Ising(North Carolina State University), Thomas Bettecken(Karolinska Institutet), Elisabeth B. Binder(Utrecht University), Florian Holsboer(Max Planck Institute of Psychiatry), Susanne Lucae(University of Colorado Boulder),  Bertram Müller-Myhsok (University of Toronto),  Darina Czamara(Trinity College Dublin), Martin Kohli(University of St Andrews), Manfred Uhr(University of North Carolina at Chapel Hill), Joseph Biederman(Massachusetts General Hospital), James B. Potash(University of Iowa), Donald W. Black(University of Iowa), Thomas H. Wassink(University of Southern California), William Coryell(University of Iowa),  Benjamin S Pickard(Royal Edinburgh Hospital), Kevin A. McGhee(Royal Edinburgh Hospital), Douglas Blackwood(Queen Mary University of London), Walter Muir(Royal Edinburgh Hospital), Donald J. MacIntyre(Royal Edinburgh Hospital), Alan McLean(King's College London), Andrew M. McIntosh(University of Michigan),  Nicholas J Schork (Scripps Research Institute), Cinnamon S. Bloss(Scripps Research Institute),  Erin N Smith(Scripps Research Institute), Cinnamon S. Bloss(Scripps Research Institute), Peng Zhang(Howard University), Laura J. Scott(University of Michigan), Michael Boehnke(Geisinger Medical Center), Phoenix Kwan(University of Michigan),  Sebastian Zöllner(Feinstein Institute for Medical Research), Matthew Flickinger(University of Würzburg), Weihua Guan(University of Minnesota), Peng Zhang(King's College London), Laura J. Scott(University of Michigan), Michael Boehnke(University of Michigan), Phoenix Kwan(University of Michigan),  Sebastian Zöllner(University of North Carolina at Chapel Hill), Matthew Flickinger(University of Michigan), Weihua Guan(University of Minnesota),  Gonneke Willemsen(Amsterdam Public Health),  Eco J De Geus(University of California, Los Angeles), Dorret I Boomsma(Cornell University),  Christel M Middeldorp (University of California, Los Angeles),  Jouke-Jan Hottenga(Max Planck Society), Brenda W.J.H. Penninx(Amsterdam Neuroscience),  Gonneke Willemsen(Washington University in St. Louis),  Eco J De Geus(Amsterdam Neuroscience), Dorret I Boomsma(Karolinska Institutet), Johannes H. Smit(Johns Hopkins University),  Gerard Van Grootheest (University of Bonn), Brenda W.J.H. Penninx(Feinstein Institute for Medical Research), Eco J. C. de Geus(Yale University), Dorret I Boomsma(Geisinger Medical Center),  Christel M Middeldorp (QIMR Berghofer Medical Research Institute),  Jouke-Jan Hottenga(University of Bonn), Gerome Breen(University of Dundee), Gerome Breen(King's College London), Jens Treutlein(Broad Institute), Marcella Rietschel(Heidelberg University), Jana Strohmaier(University of California, Los Angeles), Josef Frank(Heidelberg University), Stephanie H. Witt(King's College London), Sandra Meier(Heidelberg University), René Breuer(Heidelberg University), Richard Bruggeman(University Medical Center Groningen), Nancy G. Buccola(Louisiana State University Health Sciences Center New Orleans), Jan K. Buitelaar(National Institutes of Health), Barbara Franke(Radboud University Nijmegen), William E. Bunney(University of California, Irvine), Joseph D. Buxbaum(University of Southern California), Steven P. Hamilton(University of California, San Francisco), William Byerley(University of California, San Francisco), William Byerley(University of California, San Francisco), Sian Caesar(University of Michigan), Lisa Jones(University of Birmingham), Katherine Gordon‐Smith(Cardiff Council), Wiepke Cahn(University Medical Center Utrecht), René S. Kahn(University Medical Center Utrecht), Rita M. Cantor(Universitat de València), Marta Ribasés(Tufts University), Miguel Casas(Universitat Autònoma de Barcelona), Josep Antoni Ramos‐Quiroga(Broad Institute), Miguel Casas(Universitat Autònoma de Barcelona), Josep Antoni Ramos‐Quiroga(Universitat Autònoma de Barcelona), Sven Cichon(University of Bonn),  Franziska Degenhardt(University of Bonn),  Stefan Herms(University of Bonn), Thomas W. Mühleisen(University of Bonn),  Markus M Nöthen(University of Bonn), Sven Cichon(University of Bonn), Sven Cichon(University of Bonn),  Franziska Degenhardt(University of Bonn), Johannes Schumacher(University of Bonn), Manuel Mattheisen(University of Bonn), Thomas W. Mühleisen(University of Bonn), Peter Propping(University of Bonn),  Markus M Nöthen(University of Bonn),  Stefan Herms(University of Bonn), Sven Cichon (University of Bonn), C. Robert Cloninger(University of Groningen), Alexandre A. Todorov(University of Bonn), Michele L. Pergadia(Washington University in St. Louis), Andrew C. Heath(Howard University), Pamela A. F. Madden(Washington University in St. Louis), Edwin H. Cook(Broad Institute), William M. McMahon(University of Utah), Hilary Coon(University of Utah), Bru Cormand(Centre for Biomedical Network Research on Rare Diseases), Bru Cormand(University of Copenhagen), Bru Cormand(University of California, Los Angeles), David W. Craig(Translational Genomics Research Institute), Szabocls Szelinger(Translational Genomics Research Institute), Russell Schachar(Hospital for Sick Children), Jennifer Crosbie(Hospital for Sick Children), Margaret A. Pericak‐Vance(University of Miami), Michael L. Cuccaro(University of Southern California), David Curtis(University of Southern California), Darina Czamara (Munich Cluster for Systems Neurology),  Bertram Müller-Myhsok(Washington University in St. Louis), Susmita Datta(University of Miami), Géraldine Dawson(Autism Speaks), Géraldine Dawson(Autism Speaks), Joseph Piven(University of North Carolina at Chapel Hill), Géraldine Dawson(Autism Speaks), K. Matthews(University of Iowa), Richard Day(Goethe University Frankfurt), Srdjan Djurovic(Oslo University Hospital), Alysa E. Doyle(Harvard University), Jubao Duan(NorthShore University HealthSystem), Pablo V. Gejman(NorthShore University HealthSystem), Alan R. Sanders(Universitat Autònoma de Barcelona), Frank Dudbridge(University of Copenhagen), Fritz Poustka(Broad Institute), Christine M. Freitag(Goethe University Frankfurt), Eftichia Duketis(Goethe University Frankfurt), Richard P. Ebstein(University of Bonn), Howard J Edenberg(Washington University in St. Louis), Tatiana Foroud(Heidelberg University), Howard J Edenberg(Indiana University School of Medicine), Daniel L. Koller(Ghent University Hospital), John I. Nürnberger(Broad Institute), Josephine Elia(Children's Hospital of Philadelphia), Sean Ennis(University College Dublin), Stéphane Jamain(Inserm), Bruno Étain(Inserm),  Marion Leboyer(Inserm),  Stéphane Jamain (Inserm), Bruno Étain(Maine Medical Center),  Marion Leboyer(Inserm), Ayman Fanous(Georgetown University), Ayman Fanous(Georgetown University), Michael C. Neale(Virginia Commonwealth University),  Kenneth S Kendler(Rush University Medical Center), I. Nicol Ferrier(University of Pennsylvania),  Allan H Young(King's College London), Jeremy Parr(Scripps Research Institute), Éric Fombonne(Johns Hopkins University), Éric Fombonne(University of Bonn), Ann Olincy(University of Colorado Denver), Robert Freedman(Broad Institute), Stan F. Nelson(University of California, Los Angeles), Nelson B Freimer(National Institutes of Health), Roel A. Ophoff(University of California, Los Angeles), Susan L. Smalley(University of California, Los Angeles),  Sandra K Loo(University of California, Los Angeles), Ina Giegling(Mayo Clinic), Marion Friedl(University of California, Los Angeles), Annette M. Hartmann(Vrije Universiteit Amsterdam), Bettina Konte(Scripps Research Institute), Dan Rujescu(Ghent University Hospital),  Jennifer K Lowe(University of California, Los Angeles), Daniel H Geschwind (University of California, Los Angeles),  Jennifer K Lowe(Federal Institute for Drugs and Medical Devices), Daniel H Geschwind (University of California, Los Angeles), Sarah E. Medland(University of Toronto), Anjali K. Henders(QIMR Berghofer Medical Research Institute), Grant W. Montgomery(QIMR Berghofer Medical Research Institute), Dale R. Nyholt(Vanderbilt University), Nicholas G. Martin(University of Toronto), Scott D. Gordon(Translational Genomics Research Institute), Elaine Green(University of Plymouth), Caroline M. Nievergelt(University of Michigan), Tiffany A. Greenwood(Washington University in St. Louis), John R. Kelsoe(GlaxoSmithKline (United Kingdom)), Paul D. Shilling(Heidelberg University), R. Anne McKinney(Max Planck Society), Dorothy E Grice(Virginia Commonwealth University), Jeremy M. Silverman(Vrije Universiteit Amsterdam), Dorothy E Grice (Maastricht University), Susanne Hoefels(University of Bonn), Wolfgang Maier(Nationwide Children's Hospital), Magdalena Groß(University of Bonn), Weihua Guan(University of Minnesota), Lieuwe de Haan(Harvard University Press), Jonathan L. Haines(University of Iowa), Håkon Håkonarson(Children's Hospital of Philadelphia), Håkon Håkonarson(Children's Hospital of Philadelphia), Joachim Hallmayer(University of Copenhagen),  Valentina Moskvina(University of Bonn), Marian L. Hamshere(University of Washington), Peter Holmans(Cardiff Council), Henrik Berg Rasmussen(Roskilde University), Line Olsen(Roskilde University), Andrés Ingason(Roskilde University), Thomas Folkmann Hansen(Roskilde University),  Thomas Werge(Roskilde University), Henrik Berg Rasmussen(Roskilde University), Line Olsen(Roskilde University), Andrés Ingason(Roskilde University), Manuel Mattheisen(University of Bonn), Thomas Folkmann Hansen(Roskilde University),  Thomas Werge(Roskilde University), Martin Hautzinger(University of Pittsburgh), Ian B. Hickie(The University of Sydney), Evaristus Nwulia(Howard University), William Lawson(Broad Institute), Maria Hipolito(Howard University), Witte J.G. Hoogendijk(Erasmus MC), Vanessa Hus(University of North Carolina at Chapel Hill), Edward G. Jones(Broad Institute), Jung-Ying Tzeng(North Carolina State University), Matthew C. Keller(The University of Queensland), James L. Kennedy(Centre for Addiction and Mental Health), Lindsey Kent(University of St Andrews), Patrick F. Sullivan(University of North Carolina at Chapel Hill), Yunjung Kim(University of North Carolina at Chapel Hill), Sabine M. Klauck(German Cancer Research Center), Lambertus Klei(University of Pittsburgh), Bernie Devlin(University of Pittsburgh), James A. Knowles(University of Southern California), Carlos N. Pato(University of Southern California), Helena Medeiros(University of Southern California), Michele T. Pato(University of Southern California), Ania Korszun(Queen Mary University of London), Jim van Os(Maastricht University Medical Centre), Inez Myin‐Germeys(Maastricht University Medical Centre), Lydia Krabbendam(Maastricht University Medical Centre), Mikael Landén(Karolinska Institutet), Mark Lathrop(Centre National de Recherche en Génomique Humaine),  Christa L Martin(Autism & Developmental Medicine Institute), David H. Ledbetter(Autism & Developmental Medicine Institute),  Anil K Malhotra(Albert Einstein College of Medicine), Todd Lencz (Albert Einstein College of Medicine),  Anil K Malhotra(Albert Einstein College of Medicine), Todd Lencz (Albert Einstein College of Medicine),  Anil K Malhotra(Albert Einstein College of Medicine), Todd Lencz (Albert Einstein College of Medicine), Klaus-Peter Lesch(University of Würzburg), Klaus-Peter Lesch(University of Würzburg), Douglas F. Levinson(Stanford University), Jun Z. Li(University of Michigan), Patrick J. McGrath(New York Psychoanalytic Society and Institute), Jeffrey A. Lieberman(New York Psychoanalytic Society and Institute), Dan-Yu Lin(University of North Carolina at Chapel Hill), Don Linszen(University of Amsterdam), Chunyu Liu(University of Illinois Chicago), Susan L. Smalley(University of California, Los Angeles), Sandra K Loo (University of California, Los Angeles), Catherine Lord(Cornell University), Elena Maestrini(University of Bologna), Pamela B. Mahon(Johns Hopkins University), Thomas G. Schulze(Johns Hopkins University), Shrikant Mane(Genomas (United States)), Manuel Mattheisen(University of Bonn), Manuel Mattheisen(University of Bonn), Morten Mattingsdal(University of Oslo), James J. McGough(University of California, Los Angeles),  Sebastian Zöllner(University of Michigan), Peng Zhang(University of Michigan), Melvin G. McInnis(University of Michigan),  Benjamin S Pickard(Royal Edinburgh Hospital), Alan McLean(Royal Edinburgh Hospital), Andrew M. McIntosh(Royal Edinburgh Hospital), Walter Muir(Royal Edinburgh Hospital), Francis J. McMahon(National Institutes of Health), Jobst Meyer(Universität Trier), Lefkos Middleton(Imperial College London), Vihra Milanova, Ana Miranda(Universitat de València), Anthony P. Monaco(Tufts University), Anthony P. Monaco(Tufts University),  Matthew State(Yale University), Daniel Moreno‐De‐Luca(Yale University),  Stephan J Sanders (Yale University), Gunnar Morken(Norwegian University of Science and Technology), Gunnar Morken(Norwegian University of Science and Technology), Eric M Morrow(Brown University), Eric M Morrow(Brown University), Pierandrea Muglia(GlaxoSmithKline (Italy)), Federica Tozzi(GlaxoSmithKline (Italy)), Thomas W. Mühleisen(University of Bonn),  A Jeremy Willsey(Yale University), Michael T. Murtha(Yale University),  Stephan J Sanders(Yale University),  Matthew State (Yale University), Vishwajit L. Nimgaonkar(University of Pittsburgh), Vishwajit L. Nimgaonkar(University of Pittsburgh), Willem A. Nolen(University Medical Center Groningen), John I. Nürnberger(Indiana University School of Medicine), Robert D. Oades(University of Duisburg-Essen), Guiomar Oliveira(Hospitais da Universidade de Coimbra), Roel A. Ophoff(University of California, Los Angeles), Roel A. Ophoff(University of California, Los Angeles), Aarno Palotie(Wellcome Sanger Institute), Karola Rehnström(Wellcome Sanger Institute), Andrew D Paterson(University of Toronto), Andrew D Paterson (University of Toronto), Wei Xu(University of Toronto), Johannes H. Smit(Amsterdam Public Health),  Gerard Van Grootheest(Amsterdam Public Health), Brenda W.J.H. Penninx(Amsterdam Neuroscience), Danielle Posthuma(Erasmus MC), Danielle Posthuma(Erasmus MC), Danielle Posthuma(Erasmus MC), Digby Quested(University of Oxford), Andreas Reif(University of Würzburg), Marta Ribasés(Centro de Investigación Biomédica en Red de Salud Mental), John P. Rice(Washington University in St. Louis), Kathryn Roeder(Carnegie Mellon University), Herbert Roeyers(Ghent University Hospital), Edmund Sonuga‐Barke(Ghent University Hospital), Aribert Rothenberger, Guy A. Rouleau(McGill University), Stephan J Sanders(Yale University),  A Jeremy Willsey(Yale University),  Matthew State (Yale University), Stephan J Sanders(Yale University), Susan L. Santangelo(Harvard University), Susan L. Santangelo(Harvard University), Joseph A. Sergeant, Alan F. Schatzberg(Stanford University), William A. Scheftner(Rush University Medical Center), Gerard D. Schellenberg(University of Pennsylvania), Stephen W. Scherer(Hospital for Sick Children),  Erin N Smith(Scripps Research Institute), Nicholas J Schork (Scripps Research Institute), Thomas G. Schulze(Johns Hopkins University), Markus Schwarz, Jianxin Shi(National Cancer Institute), Stanley I. Shyn(University of Washington), Susan L. Slager(Mayo Clinic), Edmund Sonuga‐Barke(Ghent University Hospital), David St Clair(University of Aberdeen), Michael Steffens(Federal Institute for Drugs and Medical Devices), Hans-Christoph Steinhausen(University of Basel), Hans-Christoph Steinhausen(University of Basel), Hans-Christoph Steinhausen(University of Basel), John S. Strauss(Centre for Addiction and Mental Health), John B. Vincent(Centre for Addiction and Mental Health), T. Scott Stroup(Columbia University), James S. Sutcliffe(Vanderbilt University), Péter Szatmári(Centre for Addiction and Mental Health), Péter Szatmári(Centre for Addiction and Mental Health), Péter Szatmári(Centre for Addiction and Mental Health), Srinivasa Thirumalai(Oxford Health NHS Foundation Trust), Edwin J.C.G. van den Oord(Virginia Commonwealth University), Astrid M Vicente(University of Lisbon), Astrid M. Vicente(University of Lisbon), Astrid M Vicente(University of Lisbon), Veronica J. Vieland(Nationwide Children's Hospital), Peter M Visscher(The University of Queensland), Christopher A Walsh(Boston Children's Hospital), Christopher A Walsh(Boston Children's Hospital), Christopher A. Walsh(Boston Children's Hospital), Christopher A. Walsh(Boston Children's Hospital), Myrna M. Weissman(Columbia University), Thomas Werge(Roskilde University), Thomas F. Wienker(University of Bonn), Ellen M Wijsman(University of Washington), Ellen M Wijsman(University of Washington), Allan H Young(King's College London), Timothy W. Yu(Boston Children's Hospital), Peter P. Zandi(Johns Hopkins University), Frans G. Zitman(Leiden University Medical Center), John R. Kelsoe(University of California San Diego), Kenneth S Kendler(Virginia Commonwealth University), Kenneth S Kendler(Virginia Commonwealth University)
Nature Genetics
August 11, 2013
Cited by 2,346Open Access
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