Alzheimer's Disease--Genotypes, Phenotype, and Treatments

Dennis J. Selkoe(Brigham and Women's Hospital)
Science
January 31, 1997
10.1126/science.275.5300.630
Cited by 879

Abstract

What causes Alzheimer's disease? Selkoe's Perspective reviews recent research identifying four different genetic causes of Alzheimer's disease and suggests that all four point toward the deposition of amyloid beta in the brain as the initial trigger for the disease.

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