A Nedd8 conjugation pathway is essential for proteolytic targeting of p27 <sup>Kip1</sup> by ubiquitination

Vladimir N. Podust, Vincent Chau(Eli Lilly (United States)), Michael B. Coggins(KalVista Pharmaceuticals (United States)), Jacqueline W. Pierce(KalVista Pharmaceuticals (United States)), Chun‐Hua Wang(Taipei Tzu Chi Hospital), Rong-Shu Luo(KalVista Pharmaceuticals (United States)), Eric S. Lightcap(Minneapolis Business College), Tatiana Gladysheva(KalVista Pharmaceuticals (United States)), James E. Brownell(AstraZeneca (United States))
Proceedings of the National Academy of Sciences
April 18, 2000
10.1073/pnas.090465597
Cited by 245

Related Papers

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
|Nature|2009|2k
Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27
|Science|1995|1.8k
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
|Nature Cell Biology|2000|1.6k
A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein
|Science|1989|1.5k
Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.
|Proceedings of the National Academy of Sciences|1987|621