PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
William J. Israelsen(Massachusetts Institute of Technology), Talya L. Dayton(Massachusetts Institute of Technology), Shawn M. Davidson(Massachusetts Institute of Technology), Brian P. Fiske(Massachusetts Institute of Technology), Aaron M. Hosios(Massachusetts Institute of Technology), Gary Bellinger(Massachusetts Institute of Technology), Jie Li(The University of Texas MD Anderson Cancer Center), Yimin Yu(Massachusetts Institute of Technology), Mika Sasaki(Beth Israel Deaconess Medical Center), James W. Horner(Dana-Farber Cancer Institute), Laura N. Burga(Beth Israel Deaconess Medical Center), Jianxin Xie(Cell Signaling Technology (United States)), Michael J. Jurczak(Yale University), Ronald A. DePinho(Dana-Farber Cancer Institute), Clary B. Clish(Broad Institute), Tyler Jacks(Massachusetts Institute of Technology), Richard G. Kibbey(Yale University), Gerburg M. Wulf(Beth Israel Deaconess Medical Center), Dolores Di Vizio(Cedars-Sinai Medical Center), Gordon B. Mills(The University of Texas MD Anderson Cancer Center), Lewis C. Cantley(Beth Israel Deaconess Medical Center), Matthew G. Vander Heiden(Dana-Farber Cancer Institute)
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Abstract
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