THE MECHANICS OF BREATHING IN NORMAL SUBJECTS AND IN PATIENTS WITH CARDIOPULMONARY DISEASE

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Article1 June 1958THE MECHANICS OF BREATHING IN NORMAL SUBJECTS AND IN PATIENTS WITH CARDIOPULMONARY DISEASEERNST O. ATTINGER, M.D., MERRILL M. GOLDSTEIN, M.D., MAURICE S. SEGAL, M.D., F.A.C.P.ERNST O. ATTINGER, M.D.Search for more papers by this author, MERRILL M. GOLDSTEIN, M.D.Search for more papers by this author, MAURICE S. SEGAL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-6-1269 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA number of reports have appeared during recent years on the changes of the physical properties of the lung in cardiopulmonary diseases.1-26 Valuable new information has been obtained on the fundamental nature of different disorders, though only a comparatively small number of subjects have been studied. It is the purpose of this report to describe the results on a series of 100 subjects: 25 normal subjects and 75 patients with various types of cardiopulmonary disease.MATERIAL AND METHODSThe subjects were studied in the basal state and in the supine position. Transpulmonary pressures, instantaneous air flow rates and tidal volumes...Bibliography1. MeadWhittenberger JJL: Physical properties of human lungs measured during spontaneous respiration, J. Appl. Physiol. 5: 779, 1953. CrossrefGoogle Scholar2. McIlroyMarshallChristie MBRRV: The work of breathing in normal subjects, Clin. Sc. 13: 127, 1954. MedlineGoogle Scholar3. DuBoisBotelhoComroe ABSYJH: A new method for measuring airway resistance in man using a body plethysmograph: values in normal subjects and in patients with respiratory disease, J. Clin. Investigation 35: 327, 1956. CrossrefMedlineGoogle Scholar4. FrankMeadSiebensStorey NRJAACF: Measurement of pulmonary compliance in 70 healthy young adults, J. Appl. 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Bernstein L: The discontinuity in the pressure-volume curve of the rabbit's lung, J. Physiol. 124: 35, 1954. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ERNST O. ATTINGER, M.D.; MERRILL M. GOLDSTEIN, M.D.; MAURICE S. SEGAL, M.D., F.A.C.P.Affiliations: Boston, Massachusetts*Received for publication May 1, 1957.From the Department of Medicine, Tufts University School of Medicine, and the Lung Station (Tufts) and Department of Inhalation Therapy, Boston City Hospital, Boston, Massachusetts.†Work done during tenure of a Research Fellowship of the American Heart Association.Requests for reprints should be addressed to Maurice S. Segal, M.D., Department of Inhalation Therapy, Boston City Hospital, Boston 18, Massachusetts. 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