Leaderboards/Virus-based gene therapy research

Virus-based gene therapy research

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Samagya Banskota
Broad Institute
2
Meirui An
Broad Institute
3
Fernando P. Canale
University of Zurich
4
Jessie R. Davis
Broad Institute
5
Mitchell L. Leibowitz
Broad Institute
6
Mohammadsharif Tabebordbar
Broad Institute
7
Jordan L. Doman
Broad Institute
8
David Goertsen
Pasadena City College
9
Huawei Tong
Chinese Academy of Sciences
10
Martino Alfredo Cappelluti
The San Raffaele Telethon Institute for Gene Therapy

Papers

1
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
Nature Biotechnology|2024
236 cit.
2
Durable and efficient gene silencing in vivo by hit-and-run epigenome editing
Nature|2024
177 cit.
3
Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase
Nature Communications|2024
49 cit.
4
Publication in Nature Medicine (2025) [39 citations, W4406374689]
Nature Medicine|2025
39 cit.
5
Programmable G-to-Y base editing using engineered DNA glycosylase
Life Medicine|2024
1 cit.
6
Publication in Digital Access to Scholarship at Harvard (DASH) (Harvard University) (2025) [W7133581441]
Digital Access to Scholarship at Harvard (DASH) (Harvard University)|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Macaya Douoguih
Johnson & Johnson (Netherlands)
2
Elizabeth J. Hong
California Institute of Technology
3
Arati Desai
University of Pennsylvania
4
MacLean P. Nasrallah
University of Pennsylvania
5
Philipp Isermann
Cornell University
6
Rachel M. Gilbert
Mayo Clinic
7
Kosuke Murakami
University of Tsukuba
8
Xue-Wen Wang
Beijing University of Chinese Medicine
9
Baek Kim
Leeds Teaching Hospitals NHS Trust
10
Tanglong Yuan
Agricultural Genomics Institute at Shenzhen

Papers

1
Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S
New England Journal of Medicine|2022
250 cit.
2
Machine learning for cryosection pathology predicts the 2021 WHO classification of glioma
Med|2023
60 cit.
3
Impact of Preexisting Anti–Adenovirus 26 Humoral Immunity on Immunogenicity of the Ad26.COV2.S Coronavirus Disease 2019 Vaccine
The Journal of Infectious Diseases|2022
30 cit.
4
Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes
Cell Discovery|2024
22 cit.
5
Evaluation of Heat Inactivation of Human Norovirus in Freshwater Clams Using Human Intestinal Enteroids
Viruses|2022
20 cit.
6
Parallel encoding of CO2 in attractive and aversive glomeruli by selective lateral signaling between olfactory afferents
Current Biology|2022
20 cit.
7
Chronic exposure to odors at naturally occurring concentrations triggers limited plasticity in early stages of Drosophila olfactory processing
eLife|2023
18 cit.
8
The MARECA (national study of management of breast cancer locoregional recurrence and oncological outcomes) study: National practice questionnaire of United Kingdom multi-disciplinary decision making
European Journal of Surgical Oncology|2022
12 cit.
9
Olfactory coding
Current Biology|2022
10 cit.
10
Long-Term Clinical Safety of the Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: A Prospective, Multi-Country, Observational Study
Vaccines|2024
7 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
James M. Wilson
St Bartholomew's Hospital
2
Bernard Moss
National Institute of Allergy and Infectious Diseases
3
Mark A. Kay
Io Therapeutics (United States)
4
Peter M. Howley
Harvard University
5
Luigi Naldini
Vita-Salute San Raffaele University
6
David Baltimore
California Institute of Technology
7
R. Jude Samulski
University of North Carolina at Chapel Hill
8
Phillip A. Sharp
Allen Institute
9
Thomas Shenk
Princeton University
10
Robert A. Weinberg
Whitehead Institute for Biomedical Research

Papers

1
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
Cell|2008
8.7k cit.
2
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
Science|1996
4.9k cit.
3
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
Proceedings of the National Academy of Sciences|2006
4.3k cit.
4
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
Cell|1990
4k cit.
5
Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis
Cell|2004
3.8k cit.
6
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
Cell|2005
3.7k cit.
7
A Third-Generation Lentivirus Vector with a Conditional Packaging System
Journal of Virology|1998
3.4k cit.
8
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
Nature|2007
3.2k cit.
9
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
Science|1996
3.1k cit.
10
NF-κB: Ten Years After
Cell|1996
3k cit.

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