Leaderboards/TGF-β signaling in diseases

TGF-β signaling in diseases

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Anna O. Giarratana
University of Wisconsin–Madison
2
Xin Xin
Washington State University
3
Zheng-Jie Chia
Griffith University
4
Hanqiang Deng
Yale University
5
Łukasz Wieteska
University of Leeds
6
Anna M. Kolarzyk
Cornell University
7
Claudio Humeres
Albert Einstein College of Medicine
8
Siru Zhou
Southwest Petroleum University
9
Steven B. Heymsfield
Pennington Biomedical Research Center
10
Christina J. Su
California Institute of Technology

Papers

1
TGF-β signaling: critical nexus of fibrogenesis and cancer
Journal of Translational Medicine|2024
120 cit.
2
The Role of TGF-β/SMAD Signaling in Hepatocellular Carcinoma: from Mechanism to Therapy and Prognosis
International Journal of Biological Sciences|2024
84 cit.
3
Fibroblast Smad7 Induction Protects the Remodeling Pressure-Overloaded Heart
Circulation Research|2024
34 cit.
4
A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling
Nature Cardiovascular Research|2024
14 cit.
5
cSTAR analysis identifies endothelial cell cycle as a key regulator of flow-dependent artery remodeling
Science Advances|2025
14 cit.
6
FOXO1 Integrates Endothelial Hemodynamic, Inflammatory, and Metabolic Pathways in Atherosclerosis
Circulation Research|2026
6 cit.
7
Publication in Research and Practice in Thrombosis and Haemostasis (2025) [3 citations, W4411176129]
Research and Practice in Thrombosis and Haemostasis|2025
3 cit.
8
Publication in Circulation (2024) [W4404324121]
Circulation|2024
0 cit.
9
Publication in Journal of Plant Registrations (2024) [W4405606270]
Journal of Plant Registrations|2024
0 cit.
10
Publication in Journal of Nuclear Cardiology (2025) [W4413782207]
Journal of Nuclear Cardiology|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Wei Mu
Shanghai Jiao Tong University
2
Xiao‐Fan Wang
Duke University
3
Thomas Schürpf
Akebia Therapeutics (United States)
4
Shin Han Tsai
Taipei Medical University
5
Kristina H. Young
Providence Portland Medical Center
6
David A. George
Nuffield Orthopaedic Centre
7
Jianwei Lv
Second Military Medical University
8
Charles E. Birse
Quest Diagnostics (United States)
9
Ina Felau
National Cancer Institute
10
John A. Demchok
National Cancer Institute

Papers

1
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
Nature Cell Biology|2022
325 cit.
2
Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial
The Lancet Oncology|2022
142 cit.
3
Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype
Advanced Science|2023
25 cit.
4
Antagonizing the irreversible thrombomodulin-initiated proteolytic signaling alleviates age-related liver fibrosis via senescent cell killing
Cell Research|2023
19 cit.
5
Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response
Nature Communications|2024
15 cit.
6
Correlation of serum circulating testosterone levels with stress urinary incontinence in postmenopausal women
World Journal of Urology|2023
8 cit.
7
Optimizing the procedure for manufacturing clinical-grade genetically manipulated natural killer cells for adoptive immunotherapy
Cytotherapy|2024
6 cit.
8
Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes
Scientific Reports|2024
5 cit.
9
Facilitating Mental Health Treatment Through Proactive Screening and Concierge Services in the Workplace
Journal of Occupational and Environmental Medicine|2022
3 cit.
10
Impact of a Digital Diabetes Prevention Program on Estimated 8-Year Risk of Diabetes in a Workforce Population
Journal of Occupational and Environmental Medicine|2022
2 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Joan Massagué
Memorial Sloan Kettering Cancer Center
2
Rik Derynck
University of California, San Francisco
3
Peter ten Dijke
Leiden University Medical Center
4
Kohei Miyazono
The University of Tokyo
5
Jeffrey L. Wrana
University of Toronto
6
Ernesto Canalis
UConn Health
7
Xu Cao
First Hospital of China Medical University
8
Carlos L. Arteaga
The University of Texas Southwestern Medical Center
9
Caroline S. Hill
The Francis Crick Institute
10
Valerie M. Weaver
University of California, San Francisco

Papers

1
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Cell|2009
4k cit.
2
Tensional homeostasis and the malignant phenotype
Cancer Cell|2005
3.9k cit.
3
Genes that mediate breast cancer metastasis to lung
Nature|2005
3k cit.
4
A multigenic program mediating breast cancer metastasis to bone
Cancer Cell|2003
2.6k cit.
5
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
Journal of Biological Chemistry|1986
2.5k cit.
6
Mechanism of activation of the TGF-β receptor
Nature|1994
2.3k cit.
7
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
Cell|1994
2.1k cit.
8
Genes that mediate breast cancer metastasis to the brain
Nature|2009
1.9k cit.
9
Endogenous human microRNAs that suppress breast cancer metastasis
Nature|2008
1.9k cit.
10
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
Nature|1997
1.8k cit.

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