Leaderboards/Synthesis and Reactions of Organic Compounds

Synthesis and Reactions of Organic Compounds

Last updated July 7, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
Martha Mantzanidou
Aristotle University of Thessaloniki
2
Reda G. Yousef
Al-Azhar University
3
Heyun Sheng
Nanyang Normal University
4
Qian Wang
Nanjing Forestry University
5
Anjaly Das
National Institute of Technology Calicut
6
S. B. THAKUR
National Institute of Technology Jamshedpur
7
Shawn E. Wright
Fate Therapeutics (United States)
8
Anna Kowalczyk
Medical University of Lodz
9
Ahmad J. Almalki
King Abdulaziz University
10
Mohammed M. Alanazi
Northern Border University

Rising Stars Papers

1
FDA approved fluorine-containing drugs in 2023
Chinese Chemical Letters|2024
78 cit.
2
Palladium-Catalyzed Difluorocarbene Transfer Enabled Divergent Synthesis of γ-Butenolides and Ynones from Iodobenzene and Terminal Alkynes
Journal of the American Chemical Society|2024
47 cit.
3
Biological and computational assessment of new synthesized nicotinamides as potential immunomodulatory VEGFR-2 inhibitors
Journal of Molecular Structure|2024
14 cit.
4
Design, synthesis, and mechanistic evaluation of novel benzimidazole-hydrazone compounds as dual inhibitors of EGFR and HER2: Promising candidates for anticancer therapy
Journal of Molecular Structure|2024
14 cit.
5
Design and synthesis of new nicotinamides as immunomodulatory VEGFR-2 inhibitors and apoptosis inducers
Future Medicinal Chemistry|2024
6 cit.
6
Brain-derived neurotrophic factor (BDNF) Single nucleotide gene polymorphism and Nerve growth factor are risk factors that increase the severity of Allergic Rhinitis
Egyptian Journal of Chemistry|2024
3 cit.
7
Discovery of new thieno[2,3-d]pyrimidine-based dual VEGFR-2 and EGFR inhibitors for enhanced therapeutic efficacy in breast cancer
Journal of Molecular Structure|2025
3 cit.
8
Synthesis of N-sulfenylimines via an electrochemical radical coupling of amines and thiols mediated by bromide ions
Tetrahedron|2024
2 cit.
9
Modulatory effects of oxytocin on normal human cultured melanocyte proliferation, migration, and melanogenesis
Tissue and Cell|2024
2 cit.
10
Radical [3+2] cycloaddition enables polysubstituted pyrrole synthesis <i>via</i> a visible-light-mediated reaction
Chemical Communications|2025
2 cit.

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Sigal Saphier
Israel Institute for Biological Research
2
Eytan Gershonov
Israel Institute for Biological Research
3
Chuanle Zhu
South China Agricultural University
4
Vinod Mokale
Samjin Pharm (South Korea)
5
Yalda Zolghadri
Shiraz University
6
Fa‐Guang Zhang
Tianjin University
7
Xiao‐Song Xue
Shanghai Institute of Organic Chemistry
8
Sergei A. Shipilovskikh
ITMO University
9
David Jonathan Bennett
Merck & Co., Inc., Rahway, NJ, USA (United States)
10
Eman A. E. El‐Helw
Ain Shams University

Emerging Leaders Papers

1
The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets
British Journal of Pharmacology|2023
213 cit.
2
Synthesis of thieno[3,2-e]pyrrolo[1,2-a]pyrimidine derivatives and their precursors containing 2-aminothiophenes fragments as anticancer agents for therapy of pulmonary metastatic melanoma
European Journal of Medicinal Chemistry|2023
50 cit.
3
Synthesis and in silico studies of certain benzo[f]quinoline-based heterocycles as antitumor agents
Scientific Reports|2024
42 cit.
4
Synthesis, insecticidal Activity, and molecular docking analysis of some benzo[h]quinoline derivatives against Culex pipiens L. Larvae
Bioorganic Chemistry|2024
41 cit.
5
Synthesis and Antimicrobial Activity of Thiophene-Based Heterocycles Derived from Thiophene-2-Carbohydrazide
Future Medicinal Chemistry|2024
38 cit.
6
Synthesis and cytotoxicity evaluation of novel 1,8-acridinedione derivatives bearing phthalimide moiety as potential antitumor agents
Scientific Reports|2023
37 cit.
7
Synthesis, analgesic and antimicrobial activity of substituted 2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylamino)-4-oxo-4-phenylbut-2-enoates
Russian Chemical Bulletin|2022
31 cit.
8
Quadruple Functionalized Pyrazole Pharmacophores by One‐pot Regioselective [3+2] Cycloaddition of Fluorinated Nitrile Imines and Dicyanoalkenes
Chemistry - An Asian Journal|2022
31 cit.
9
Synthesis, Intramolecular Cyclization, and Analgesic Activity of Substituted 2-[2-(Furancarbonyl)hydrazinylydene]-4-oxobutanoic Acids
Russian Journal of General Chemistry|2022
28 cit.
10
Synthesis and Antinociceptive Activity of Substituted 2-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thiophene-2-ylamino)-4-oxobut-2-enoates
Russian Journal of General Chemistry|2022
27 cit.

Current Senior Leaders

Established & currently active

Current Senior Leaders Researchers

1
José Elguero
Instituto de Química Médica
2
Jinbo Hu
University of Science and Technology of China
3
Alan R. Katritzky
King Abdulaziz University
4
Norio Shibata
Nagoya Institute of Technology
5
Jean’ne M. Shreeve
University of Idaho
6
Marcos A. P. Martins
Universidade Federal de Santa Maria
7
Heinz Heimgartner
University of Zurich
8
Frédéric R. Leroux
Centre National de la Recherche Scientifique
9
Олег Н. Чупахин
Ural Federal University
10
Marko Zupan
University of Ljubljana

Current Senior Leaders Papers

1
Behavior of Ylides Containing N, O, and C Atoms as Hydrogen Bond Acceptors
Journal of the American Chemical Society|2000
1.7k cit.
2
Energetic Nitrogen‐Rich Salts and Ionic Liquids
Angewandte Chemie International Edition|2006
783 cit.
3
Recent progress in the synthesis of 1,2,3,4,-tetrahydroquinolines
Tetrahedron|1996
704 cit.
4
Selective difluoromethylation and monofluoromethylation reactions
Chemical Communications|2009
651 cit.
5
Aromaticity: a Theoretical Concept of Immense Practical Importance
Tetrahedron|2000
535 cit.
6
Interaction of Anions with Perfluoro Aromatic Compounds
Journal of the American Chemical Society|2002
526 cit.
7
Fused heterocycle-based energetic materials (2012–2019)
Journal of Materials Chemistry A|2020
471 cit.
8
Aromaticity as a quantitative concept. 1. A statistical demonstration of the orthogonality of classical and magnetic aromaticity in five- and six-membered heterocycles
Journal of the American Chemical Society|1989
459 cit.
9
Energetic Salts with π-Stacking and Hydrogen-Bonding Interactions Lead the Way to Future Energetic Materials
Journal of the American Chemical Society|2015
459 cit.
10
Trinitromethyl-Substituted 5-Nitro- or 3-Azo-1,2,4-triazoles: Synthesis, Characterization, and Energetic Properties
Journal of the American Chemical Society|2011
407 cit.

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