Leaderboards/RNA regulation and disease

RNA regulation and disease

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Samagya Banskota
Broad Institute
2
Luke W. Koblan
Howard Hughes Medical Institute
3
Marlen C. Lauffer
Leiden University Medical Center
4
Richard de Reuver
Ghent University
5
Han Altae-Tran
McGovern Institute for Brain Research
6
Lining Zheng
University of Illinois Urbana-Champaign
7
Liron David
Ben-Gurion University of the Negev
8
Ronghong Liang
Chinese Academy of Sciences
9
Jared T. Hinkle
Johns Hopkins University
10
Yaara Finkel
Weizmann Institute of Science

Papers

1
Possibilities and limitations of antisense oligonucleotide therapies for the treatment of monogenic disorders
Communications Medicine|2024
246 cit.
2
NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks
Cell|2024
136 cit.
3
Publication in Nature Biotechnology (2024) [84 citations, W4390701847]
Nature Biotechnology|2024
84 cit.
4
High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer
Science|2025
23 cit.
5
A virally encoded high-resolution screen of cytomegalovirus dependencies
Nature|2024
20 cit.
6
Publication in Nature Communications (2025) [13 citations, W4410876846]
Nature Communications|2025
13 cit.
7
Publication in Journal of Huntington s Disease (2024) [1 citation, W4402407945]
Journal of Huntington s Disease|2024
1 cit.
8
Publication in bioRxiv (Cold Spring Harbor Laboratory) (2026) [1 citation, W7133506576]
bioRxiv (Cold Spring Harbor Laboratory)|2026
1 cit.
9
Publication in Biophysical Journal (2025) [W4407478263]
Biophysical Journal|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Jonathan S. Gootenberg
Brigham and Women's Hospital
2
Omar O. Abudayyeh
Brigham and Women's Hospital
3
Neeraj Salathia
University of Cambridge
4
Gwendolyn E. Kaeser
St. Charles Medical Center
5
Rizi Ai
Guangdong 999 Brain Hospital
6
Gerald Schwank
University of Zurich
7
Rich Stoner
Synthego (United States)
8
Céline Eidenschenk
Délégation Paris 5
9
Yilai Shu
Fudan University
10
Hiroshi Nishimasu
The University of Tokyo

Papers

1
Inference of CRISPR Edits from Sanger Trace Data
The CRISPR Journal|2022
839 cit.
2
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
Nature Biotechnology|2022
429 cit.
3
AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial
The Lancet|2024
325 cit.
4
In vivo prime editing of a metabolic liver disease in mice
Science Translational Medicine|2022
185 cit.
5
Rapid in silico directed evolution by a protein language model with EVOLVEpro
Science|2024
156 cit.
6
Predicting prime editing efficiency and product purity by deep learning
Nature Biotechnology|2023
146 cit.
7
Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results
Nature Medicine|2024
124 cit.
8
Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADAR
Nature Biotechnology|2022
109 cit.
9
Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor
Science Translational Medicine|2022
100 cit.
10
Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex
Cell|2022
85 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
David R. Liu
New York Hospital Queens
2
David Ron
Institute for Medical Research
3
Feng Zhang
Broad Institute
4
Jack W. Szostak
Howard Hughes Medical Institute
5
Tasuku Honjo
Kyoto University
6
Kazutoshi Mori
Kyoto University
7
Ronald C. Wek
Indiana University School of Medicine
8
Randal J. Kaufman
Discovery Institute
9
Kazuko Nishikura
The Wistar Institute
10
Peter Walter
Bay Institute

Papers

1
Multiplex Genome Engineering Using CRISPR/Cas Systems
Science|2013
15.7k cit.
2
Genome engineering using the CRISPR-Cas9 system
Nature Protocols|2013
11.7k cit.
3
In vitro selection of RNA molecules that bind specific ligands
Nature|1990
9.7k cit.
4
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Science|2013
5.5k cit.
5
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Nature|2016
5.4k cit.
6
Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation
The Journal of Experimental Medicine|2000
5.2k cit.
7
DNA targeting specificity of RNA-guided Cas9 nucleases
Nature Biotechnology|2013
4.9k cit.
8
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Cell|2015
4.9k cit.
9
Search-and-replace genome editing without double-strand breaks or donor DNA
Nature|2019
4.7k cit.
10
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
Nature|2017
4.2k cit.

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