Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

Matthew T. N. Yarnall(McGovern Institute for Brain Research), Eleonora Ioannidi(McGovern Institute for Brain Research), Cian Schmitt-Ulms(McGovern Institute for Brain Research), Rohan N. Krajeski(McGovern Institute for Brain Research), Justin Lim(McGovern Institute for Brain Research), Lukas Villiger(McGovern Institute for Brain Research), Wenyuan Zhou(McGovern Institute for Brain Research), Kaiyi Jiang(McGovern Institute for Brain Research), Sofya K. Garushyants(National Institutes of Health), Nathaniel Roberts(Integrated DNA Technologies (United States)), Liyang Zhang(Integrated DNA Technologies (United States)), Christopher A. Vakulskas(Integrated DNA Technologies (United States)), John Walker(Synthego (United States)), Anastasia P. Kadina(Synthego (United States)), Adrianna E. Zepeda(Synthego (United States)), Kevin Holden(Synthego (United States)), Hong Ma(University of Massachusetts Chan Medical School), Jun Xie(University of Massachusetts Chan Medical School), Guangping Gao(University of Massachusetts Chan Medical School), Lander Foquet(Yecuris (United States)), Greg Bial(Yecuris (United States)), Sara K. Donnelly(Phoenix (United States)), Yoshinari Miyata(Phoenix (United States)), Daniel R. Radiloff(Phoenix (United States)), Jordana M. Henderson(TriLink BioTechnologies (United States)), Andrew Ujita(TriLink BioTechnologies (United States)), Omar O. Abudayyeh(McGovern Institute for Brain Research), Jonathan S. Gootenberg(McGovern Institute for Brain Research)
Nature Biotechnology
November 24, 2022
Cited by 418Open Access
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