Leaderboards/Neurological Disease Mechanisms and Treatments

Neurological Disease Mechanisms and Treatments

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Papers

Identification of senescent, TREM2-expressing microglia in aging and Alzheimer’s disease model mouse brain

Nature Neuroscience|2024

151 cit.

Understanding the Pathophysiology of Ischemic Stroke: The Basis of Current Therapies and Opportunity for New Ones

Biomolecules|2024

146 cit.

Publication in Nature Communications (2025) [83 citations, W4406437527]

Nature Communications|2025

83 cit.

Allantoin reduces glucotoxicity and lipotoxicity in a type 2 diabetes rat model by modulating the PI3K and MAPK signaling pathways

Heliyon|2024

6 cit.

Coordination acid-engineered Prussian Blue affects glycometabolic reprogramming in microglia for epileptic treatment

Journal of Nanobiotechnology|2025

6 cit.

Publication in iScience (2024) [2 citations, W4400849734]

iScience|2024

2 cit.

Maternal and Infant Opioid Screening for Neonates at Risk

PEDIATRICS|2025

2 cit.

The Arp2/3 complex controls the development of homeostatic microglia

EMBO Reports|2026

1 cit.

Publication (2025) [W4416952428]

Unknown Journal|2025

0 cit.

Publication in Journal of Human Immunity (2025) [W4417088489]

Journal of Human Immunity|2025

0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

Katarzyna Kuter

Maj Institute of Pharmacology

Rickie Patani

National Hospital for Neurology and Neurosurgery

Lijuan Gu

Wuhan University

Tina Schwabe

Alector (United States)

Lisheng Chu

Zhejiang Chinese Medical University

Xiuzhe Wang

Shanghai Jiao Tong University

Ilaria Tassi

Alector (United States)

Nicolai Franzmeier

LMU Klinikum

Marc Suárez‐Calvet

Pasqual Maragall Foundation

Lu Xu

National Center for Supercomputing Applications

Papers

Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling pathway

Biomedicine & Pharmacotherapy|2023

237 cit.

Plasma and CSF biomarkers in a memory clinic: Head‐to‐head comparison of phosphorylated tau immunoassays

Alzheimer s & Dementia|2022

224 cit.

Tau deposition patterns are associated with functional connectivity in primary tauopathies

Nature Communications|2022

108 cit.

Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Promote Angiogenesis in Ischemic Stroke Mice via Upregulation of MiR-21-5p

Biomolecules|2022

99 cit.

Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading

Nature Communications|2022

87 cit.

Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease

Science Translational Medicine|2025

74 cit.

NOX2-mediated reactive oxygen species are double-edged swords in focal cerebral ischemia in mice

Journal of Neuroinflammation|2022

73 cit.

ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels

JAMA Neurology|2023

67 cit.

Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology

Nature Communications|2023

61 cit.

ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation

Redox Biology|2022

58 cit.

Current Senior Leaders

Wrote the book, still writing it

Papers

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

Alzheimer s & Dementia|2012

3.2k cit.

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Immunity|2017

3k cit.

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

Acta Neuropathologica|2011

2.9k cit.

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

Nature Neuroscience|2013

2.6k cit.

Silent Brain Infarcts and the Risk of Dementia and Cognitive Decline

New England Journal of Medicine|2003

2.3k cit.

Diabetes mellitus and the risk of dementia

Neurology|1999

2.1k cit.

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

Neuron|2015

2.1k cit.

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

Nature Medicine|2019

1.7k cit.

Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

The Lancet Neurology|2006

1.7k cit.

Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

JAMA|2020

1.5k cit.

Reagents for Neurological Disease Mechanisms and Treatments

Citation-validated products used in this field

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