Leaderboards/Monoclonal and Polyclonal Antibodies Research

Monoclonal and Polyclonal Antibodies Research

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Aekkachai Tuekprakhon
University of Birmingham
2
Holly Lee
University of Calgary
3
Jeffrey A. Ruffolo
Joint BioEnergy Institute
4
Martin Pačesa
SIB Swiss Institute of Bioinformatics
5
Tobias Hegelund Olsen
Age UK
6
Samuel L. Scinto
University of Delaware
7
Kathryn Westendorf
AbCellera (Canada)
8
Emily K. Makowski
University of Michigan
9
Joakim Nøddeskov Clifford
Technical University of Denmark
10
Paulina Kapłonek
Moderna Therapeutics (United States)

Papers

1
One-shot design of functional protein binders with BindCraft
Nature|2025
158 cit.
2
Designing proteins with language models
Nature Biotechnology|2024
97 cit.
3
Design of highly functional genome editors by modelling CRISPR–Cas sequences
Nature|2025
72 cit.
4
Impact of soluble BCMA and non–T-cell factors on refractoriness to BCMA-targeting T-cell engagers in multiple myeloma
Blood|2024
63 cit.
5
BCMA- or GPRC5D-targeting bispecific antibodies in multiple myeloma: efficacy, safety, and resistance mechanisms
Blood|2024
61 cit.
6
Addressing the antibody germline bias and its effect on language models for improved antibody design
Bioinformatics|2024
57 cit.
7
Reduction of monoclonal antibody viscosity using interpretable machine learning
mAbs|2024
34 cit.
8
AbEpiTope-1.0: Improved antibody target prediction by use of AlphaFold and inverse folding
Science Advances|2025
15 cit.
9
Antigen-dependent clonal sweep with sequential or combinatory anti-myeloma T cell engagers
Blood|2025
3 cit.
10
IgG4 Neutralization and Sustained Total IgG Fc-Effector Functions Following Repeated SARS-CoV-2 Vaccination with mRNA-1273
Infectious Diseases and Therapy|2026
3 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Ryan Davis
SLAC National Accelerator Laboratory
2
Joel D. Allen
University of Southampton
3
Nicholas C. Wu
University of Illinois Urbana-Champaign
4
Yihang Shen
Carnegie Mellon University
5
Denise Wootten
Monash University
6
Hejun Liu
Scripps Research Institute
7
Teemu T. Junttila
Unknown
8
Priyamvada Acharya
Duke University
9
Anni Jämsén
Science Oxford
10
Alexandra Deeks
University of Oxford

Papers

1
Structural diversity of the SARS-CoV-2 Omicron spike
Molecular Cell|2022
219 cit.
2
A large-scale systematic survey reveals recurring molecular features of public antibody responses to SARS-CoV-2
Immunity|2022
121 cit.
3
Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike
Cell Reports|2022
109 cit.
4
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation
Nature Communications|2022
84 cit.
5
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
Immunity|2023
47 cit.
6
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
Nature Communications|2023
42 cit.
7
An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies
Immunity|2024
38 cit.
8
Molecular analysis of a public cross-neutralizing antibody response to SARS-CoV-2
Cell Reports|2022
32 cit.
9
Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning
Science Advances|2022
32 cit.
10
The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2
Cell Reports|2023
32 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Timothy A. Springer
Harvard University
2
Ian A. Wilson
Raigmore Hospital
3
Jeffrey V. Ravetch
Laboratory of Molecular Genetics
4
Carolyn R. Bertozzi
Howard Hughes Medical Institute
5
Andreas Plückthun
University of Zurich
6
Ronald Levy
Hôpital Necker-Enfants Malades
7
Klaus Rajewsky
Max Delbrück Center
8
Dennis R. Burton
Scripps Research Institute
9
Erkki Ruoslahti
Sanford Burnham Prebys Medical Discovery Institute
10
Richard A. Lerner
Scripps Research Institute

Papers

1
Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule
Nature|1984
3.7k cit.
2
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
Angewandte Chemie International Edition|2009
3.1k cit.
3
A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
Journal of the American Chemical Society|2004
2.9k cit.
4
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
Nature Medicine|2000
2.7k cit.
5
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
Nature|1981
2.5k cit.
6
Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
The Journal of Immunology|1986
2.5k cit.
7
Cell Surface Engineering by a Modified Staudinger Reaction
Science|2000
2.4k cit.
8
Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
Cell|1991
2.2k cit.
9
Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model
Science|1998
2.1k cit.
10
Binding of soluble form of fibroblast surface protein, fibronectin, to collagen
International Journal of Cancer|1977
2k cit.

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