Leaderboards/Lipid metabolism and biosynthesis

Lipid metabolism and biosynthesis

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Mingyue Cao
Shandong University
2
Lianggong Ding
Nutrition Sciences (Belgium)
3
Mike Lange
University of California, Berkeley
4
Noble Kumar Talari
University of Cincinnati Medical Center
5
András Hatos
SIB Swiss Institute of Bioinformatics
6
Shizeng Pei
Central China Normal University
7
Yongjian Hu
Jinggangshan University
8
Chandana Thimme Gowda
Cedars-Sinai Medical Center
9
Gregory E. Miner
University of North Carolina at Chapel Hill
10
Sabrina Robichaud
University of Ottawa

Papers

1
Versatile organic fluorescent probes for visualizing the dynamics of lipid droplets
Coordination Chemistry Reviews|2024
84 cit.
2
Dual-Functional AIE Fluorescent Probe for Visualization of Lipid Droplets and Photodynamic Therapy of Cancer
Analytical Chemistry|2024
45 cit.
3
Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL
Nature Cell Biology|2024
32 cit.
4
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis
Nature Cell Biology|2025
29 cit.
5
Functional compartmentalization of hepatic mitochondrial subpopulations during MASH progression
Communications Biology|2025
15 cit.
6
Contact-FP: A Dimerization-Dependent Fluorescent Protein Toolkit for Visualizing Membrane Contact Site Dynamics
Contact|2024
14 cit.
7
Hepatokine ITIH3 protects against hepatic steatosis by downregulating mitochondrial bioenergetics and de novo lipogenesis
iScience|2024
13 cit.
8
Trehalose promotes atherosclerosis regression in female mice
Frontiers in Cardiovascular Medicine|2024
10 cit.
9
Protocol for monitoring fatty acid trafficking from lipid droplets to mitochondria in cultured cells
STAR Protocols|2024
2 cit.
10
Publication in Nature (2025) [2 citations, W4410161814]
Nature|2025
2 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Abdou Rachid Thiam
Centre National de la Recherche Scientifique
2
Annelie Falkevall
Karolinska Institutet
3
Ajay Singh
University of Waterloo
4
Guangle Niu
Beijing Institute of Technology
5
Constantinos V. Nikiforidis
Wageningen University & Research
6
Miguel Sánchez‐Álvarez
Instituto de Investigaciones Biomédicas Sols-Morreale
7
Martin Graef
Cornell University
8
Trevor S. Tippetts
The University of Texas Southwestern Medical Center
9
Jinqi Liu
Shanghai University of Engineering Science
10
Benjamin D. Engel
University of Basel

Papers

1
In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains
Science|2022
148 cit.
2
MemBrain: A deep learning-aided pipeline for detection of membrane proteins in Cryo-electron tomograms
Computer Methods and Programs in Biomedicine|2022
122 cit.
3
Exploiting the Twisted Intramolecular Charge Transfer Effect to Construct a Wash-Free Solvatochromic Fluorescent Lipid Droplet Probe for Fatty Liver Disease Diagnosis
Analytical Chemistry|2022
106 cit.
4
Versatile organic fluorescent probes for visualizing the dynamics of lipid droplets
Coordination Chemistry Reviews|2024
84 cit.
5
In-cell architecture of the mitochondrial respiratory chain
Science|2025
69 cit.
6
Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols
Nature Communications|2023
68 cit.
7
Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue
Journal of Hepatology|2023
64 cit.
8
Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics
The Journal of Cell Biology|2023
44 cit.
9
Extraction of oleosome and protein mixtures from sunflower seeds
Food Hydrocolloids|2023
41 cit.
10
High yield extraction of oleosins, the proteins that plants developed to stabilize oil droplets
Food Hydrocolloids|2022
38 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Bruce M. Spiegelman
Dana-Farber Cancer Institute
2
Michael S. Brown
Hospital of the University of Pennsylvania
3
Robert V. Farese
Memorial Sloan Kettering Cancer Center
4
Christoph Benning
Michigan State University
5
John Browse
Washington State University
6
Joseph L. Goldstein
Lasker Foundation
7
Rudolf Zechner
University of Graz
8
Kai Simons
Max Planck Institute of Molecular Cell Biology and Genetics
9
Lloyd M. Smith
University of Wisconsin–Madison
10
Tobias C. Walther
Memorial Sloan Kettering Cancer Center

Papers

1
Functional rafts in cell membranes
Nature|1997
9.7k cit.
2
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
Science|1993
7.5k cit.
3
Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol
Journal of Lipid Research|1964
6k cit.
4
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Nature|2012
4.7k cit.
5
Lipid Rafts As a Membrane-Organizing Principle
Science|2009
4.4k cit.
6
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
Cell|1999
4.1k cit.
7
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
Journal of Clinical Investigation|2002
4k cit.
8
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
Cell|1998
3.8k cit.
9
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
Cell|1994
3.5k cit.
10
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
Journal of Clinical Investigation|1995
3.5k cit.

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