Leaderboards/Hedgehog Signaling Pathway Studies

Hedgehog Signaling Pathway Studies

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Daniel Tylawsky
Memorial Sloan Kettering Cancer Center
2
Fabian Lim
University of California San Diego
3
Janna Puschmann
University of Münster
4
Justine Lengrand
Université Libre de Bruxelles
5
Dominique C. Hinshaw
American Society of Clinical Oncology
6
Vivien Koh
National University of Singapore
7
Maia Kinnebrew
Stanford University
8
Xiaoliang Liu
Army Medical University
9
Melissa E. Truong
University of California, San Francisco
10
Souta Motoike
Kyoto University

Papers

1
Publication in Nature (2024) [97 citations, W4390940878]
Nature|2024
97 cit.
2
Supplementary Data from Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer
Unknown Journal|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Vijay Ramaswamy
Hospital for Sick Children
2
Jie Yang
RMIT University
3
Benjamin R. Myers
Huntsman Cancer Institute
4
Young-Goo Han
St. Jude Children's Research Hospital
5
Lee F. Peng
Temple University
6
Natalie Dimier
Roche (United Kingdom)
7
Ioannis Xynos
AstraZeneca (United Kingdom)
8
Choi‐Fong Cho
Brigham and Women's Hospital
9
Mattia Mori
University of Siena
10
Hongwu Qian
University of Science and Technology of China

Papers

1
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction
Nature Structural & Molecular Biology|2022
65 cit.
2
Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1
Nature Communications|2023
48 cit.
3
Primary cilia control translation and the cell cycle in medulloblastoma
Genes & Development|2022
38 cit.
4
The Burden of Surviving Childhood Medulloblastoma: A Population-Based, Matched Cohort Study in Ontario, Canada
Journal of Clinical Oncology|2023
34 cit.
5
The Rise of Bacterial G-Quadruplexes in Current Antimicrobial Discovery
ACS Omega|2024
20 cit.
6
Structural basis for the transport and substrate selection of human urate transporter 1
Cell Reports|2024
19 cit.
7
GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade
PLoS Biology|2024
19 cit.
8
A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma
Cancers|2022
17 cit.
9
A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding
Proceedings of the National Academy of Sciences|2022
16 cit.
10
Natural Flavonoid Derivatives Have Pan-Coronavirus Antiviral Activity
Microorganisms|2023
16 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Philip A. Beachy
Stanford University
2
Andrew P. McMahon
California Institute of Technology
3
Allan Bradley
Granta Design (United Kingdom)
4
Peter B. Dirks
Hospital for Sick Children
5
Alexandra L. Joyner
Memorial Sloan Kettering Cancer Center
6
Ariel Ruiz i Altaba
University of Geneva
7
Clifford J. Tabin
Harvard University
8
Maximilian Muenke
National Institutes of Health
9
Frédéric J. de Sauvage
Gene Therapy Laboratory
10
Kathryn V. Anderson
Memorial Sloan Kettering Cancer Center

Papers

1
Identification of human brain tumour initiating cells
Nature|2004
7.4k cit.
2
Identification of a cancer stem cell in human brain tumors.
PubMed|2003
4.9k cit.
3
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Nature|1992
4.7k cit.
4
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
Nature|1996
3.1k cit.
5
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
Cell|1993
2.2k cit.
6
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
Cell|1991
2k cit.
7
Identification of Mammalian microRNA Host Genes and Transcription Units
Genome Research|2004
2k cit.
8
p63 is a p53 homologue required for limb and epidermal morphogenesis
Nature|1999
2k cit.
9
Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein
Science|1996
2k cit.
10
Requirement of <i>bic/microRNA-155</i> for Normal Immune Function
Science|2007
1.8k cit.

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