Leaderboards/Gene expression and cancer classification

Gene expression and cancer classification

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Zhuorui Xie
Icahn School of Medicine at Mount Sinai
2
Liis Kolberg
University of Tartu
3
Haotian Cui
University Health Network
4
Zuguang Gu
German Cancer Research Center
5
Ieva Rauluševičiūtė
University of Oslo
6
Gerardo Perez
University of California, Santa Cruz
7
Dylan Cable
University of Michigan
8
Giovanni Palla
Helmholtz Zentrum München
9
Áron Bartha
Semmelweis University
10
John M. Elizarraras
Baylor College of Medicine

Papers

1
scGPT: toward building a foundation model for single-cell multi-omics using generative AI
Nature Methods|2024
1k cit.
2
The UCSC Genome Browser database: 2025 update
Nucleic Acids Research|2024
579 cit.
3
WebGestalt 2024: faster gene set analysis and new support for metabolomics and multi-omics
Nucleic Acids Research|2024
371 cit.
4
Towards multimodal foundation models in molecular cell biology
Nature|2025
88 cit.
5
DeepVelo: deep learning extends RNA velocity to multi-lineage systems with cell-specific kinetics
Genome biology|2024
55 cit.
6
simona: a comprehensive R package for semantic similarity analysis on bio-ontologies
BMC Genomics|2024
13 cit.
7
Publication in Nucleic Acids Research (2024) [4 citations, W4402101332]
Nucleic Acids Research|2024
4 cit.
8
Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT
Journal of Proteome Research|2025
3 cit.
9
TNMplot: An enhanced platform for pharmacological target identification through cross‐stage and pan‐cancer gene expression analysis
British Journal of Pharmacology|2026
2 cit.
10
Two separated worlds: On the preference of influence in life science and biomedical research
Journal of Informetrics|2025
1 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Chenwei Li
Ningbo University Affiliated Hospital
2
Weizhong Chang
Frederick National Laboratory for Cancer Research
3
Daniel Blankenberg
Cleveland Clinic
4
Sanja Vicković
Science for Life Laboratory
5
Fredrik Salmén
HES-SO Genève
6
Lin Fang
BGI Group (China)
7
Hengyu Yan
China Agricultural University
8
Yue Liu
Hefei University of Technology
9
Qiang Chen
Southern University of Science and Technology
10
Sheng Yang
Ningxia University

Papers

1
DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)
Nucleic Acids Research|2022
6.3k cit.
2
High-throughput total RNA sequencing in single cells using VASA-seq
Nature Biotechnology|2022
241 cit.
3
SM-Omics is an automated platform for high-throughput spatial multi-omics
Nature Communications|2022
193 cit.
4
Spatial host–microbiome sequencing reveals niches in the mouse gut
Nature Biotechnology|2023
117 cit.
5
DAVID Ortholog: an integrative tool to enhance functional analysis through orthologs
Bioinformatics|2024
88 cit.
6
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium
Communications Biology|2022
80 cit.
7
Room-temperature co-upcycling of polyvinyl chloride and polypropylene
Nature Sustainability|2024
44 cit.
8
Effect of Crystalline Structure on the Catalytic Hydrolysis of Cellulose in Subcritical Water
ACS Sustainable Chemistry & Engineering|2022
39 cit.
9
Unveiling the mechanism for selective cleavage of C-C bonds in sugar reactions on tungsten trioxide–based catalysts
Proceedings of the National Academy of Sciences|2022
38 cit.
10
Impact of digital technology innovation on carbon emission reduction and energy rebound: Evidence from the Chinese firm level
Energy|2025
32 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Thomas D. Schmittgen
University of Florida
2
Gordon K. Smyth
The University of Melbourne
3
Jill P. Mesirov
University of California San Diego
4
David Botstein
Massachusetts Institute of Technology
5
Qing‐Yu He
Jinan University
6
Mark A. DePristo
Google (United States)
7
Wolfgang Huber
European Molecular Biology Laboratory
8
Trevor Hastie
Stanford Medicine
9
Avi Ma’ayan
Icahn School of Medicine at Mount Sinai
10
Peer Bork
Max Delbrück Center

Papers

1
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Methods|2001
181.5k cit.
2
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences|2005
56.7k cit.
3
<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data
Bioinformatics|2009
44.5k cit.
4
limma powers differential expression analyses for RNA-sequencing and microarray studies
Nucleic Acids Research|2015
43k cit.
5
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
OMICS A Journal of Integrative Biology|2012
38.3k cit.
6
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Genome Research|2010
30k cit.
7
Analyzing real-time PCR data by the comparative CT method
Nature Protocols|2008
26.7k cit.
8
HTSeq—a Python framework to work with high-throughput sequencing data
Bioinformatics|2014
22.7k cit.
9
Regularization and Variable Selection Via the Elastic Net
Journal of the Royal Statistical Society Series B (Statistical Methodology)|2005
21k cit.
10
Differential expression analysis for sequence count data
Genome biology|2010
16.4k cit.

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