Leaderboards/Galectins and Cancer Biology

Galectins and Cancer Biology

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Jianshuai Ma
Sun Yat-sen University
2
Xiaoyu Liu
Chongqing Cancer Hospital
3
Linying Jia
Xi'an Jiaotong University
4
Senhan Xu
Howard Hughes Medical Institute
5
Anna Ralser
Institute of Medical Microbiology and Hygiene
6
Klára Hánělová
Masaryk University
7
Louise Malle
Columbia University Irving Medical Center
8
Iker Ausejo‐Mauleon
Clinica Universidad de Navarra
9
Catalina Rozalén
Hospital Del Mar
10
Sashi Kandel
University of Missouri–Kansas City

Papers

1
O-GlcNAcylation reduces proteome solubility and regulates the formation of biomolecular condensates in human cells
Nature Communications|2025
12 cit.
2
Combination of locoregional radiotherapy with a TIM-3 aptamer improves survival in diffuse midline glioma models
JCI Insight|2024
7 cit.
3
Publication in Neuro-Oncology (2024) [1 citation, W4399788020]
Neuro-Oncology|2024
1 cit.
4
1277 HELICOBACTER PYLROI PROMOTES COLORECTAL CARCINOGENESIS BY DEREGULATING INTESTINAL IMMUNITY AND INDUCING A MUCUSDEGRADING MICROBIOTA SIGNATURE
Gastroenterology|2024
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Anders Mälarstig
Karolinska Institutet
2
Brian Ruffell
Moffitt Cancer Center
3
Shokrollah Elahi
University of Alberta
4
Julia Kowal
Board of the Swiss Federal Institutes of Technology
5
Yasuhiko Kizuka
Gifu University
6
Donald L. Zogg
Apple (Israel)
7
Alison C. MacKinnon
Galecto (Denmark)
8
Lukas E. Dow
Cornell University
9
Martin J. Richer
McGill University
10
Megan Y. Dennis
University of California System

Papers

1
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
Nature Biotechnology|2022
129 cit.
2
Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome
Frontiers in Immunology|2024
76 cit.
3
Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity
Cancer Cell|2024
56 cit.
4
Evaluation of CRISPR gene-editing tools in zebrafish
BMC Genomics|2022
51 cit.
5
TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8<sup>+</sup> T cell and XCR1<sup>+</sup> dendritic cell spatial co-localization
Journal for ImmunoTherapy of Cancer|2022
50 cit.
6
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
Nature Communications|2023
50 cit.
7
Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome
Journal of Autoimmunity|2024
50 cit.
8
Galectin-9 promotes natural killer cells activity via interaction with CD44
Frontiers in Immunology|2023
40 cit.
9
Analysis of SARS-CoV-2 isolates, namely the Wuhan strain, Delta variant, and Omicron variant, identifies differential immune profiles
Microbiology Spectrum|2023
38 cit.
10
Elevated ATP via enhanced miRNA-30b, 30c, and 30e downregulates the expression of CD73 in CD8+ T cells of HIV-infected individuals
PLoS Pathogens|2022
31 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Benjamin G. Neel
New York University
2
Gerald W. Hart
University of Georgia
3
Hans‐Joachim Gabius
Ludwig-Maximilians-Universität München
4
Vijay K. Kuchroo
Broad Institute
5
Nicholas K. Tonks
Cold Spring Harbor Laboratory
6
Richard D. Cummings
Beth Israel Deaconess Medical Center
7
Naoyuki Taniguchi
Osaka International Cancer Institute
8
Bruce D. Gelb
Child Health and Development Institute
9
Gabriel A. Rabinovich
Universidad de Buenos Aires
10
Avraham Raz
Wayne State University

Papers

1
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
Nature|2006
6.9k cit.
2
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
Nature Immunology|2005
2k cit.
3
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Nature|2007
1.8k cit.
4
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
Nature Genetics|2001
1.7k cit.
5
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
Cell|1995
1.7k cit.
6
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
Nature|2002
1.6k cit.
7
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
Proceedings of the National Academy of Sciences|1998
1.2k cit.
8
Induction and molecular signature of pathogenic TH17 cells
Nature Immunology|2012
1.2k cit.
9
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
Cell|1993
1.2k cit.
10
Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc.
Journal of Biological Chemistry|1984
1.1k cit.

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