Leaderboards/Extracellular vesicles in disease

Extracellular vesicles in disease

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Aleksandr Ianevski
Institute for Molecular Medicine Finland
2
Mathilde Mathieu
Åbo Akademi University
3
Yi You
Peking University
4
Manyu Chen
Wannan Medical College
5
Samantha M. Morrissey
University of Louisville
6
Thuy Giang Nguyen Cao
University Medical Center
7
Daniel Wendisch
Charité - Universitätsmedizin Berlin
8
Konrad Hoeft
RWTH Aachen University
9
Fernanda G. Kugeratski
The University of Texas MD Anderson Cancer Center
10
Daan J. Kloosterman
Oncode Institute

Papers

1
Macrophage-mediated myelin recycling fuels brain cancer malignancy
Cell|2024
187 cit.
2
Publication in Advanced Materials (2024) [134 citations, W4391165155]
Advanced Materials|2024
134 cit.
3
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Nature Communications|2024
50 cit.
4
Publication in European Heart Journal (2025) [47 citations, W4406617626]
European Heart Journal|2025
47 cit.
5
Publication in ACS Nano (2025) [40 citations, W4406805807]
ACS Nano|2025
40 cit.
6
Nanoengineered cargo with targeted in vivo Foxo3 gene editing modulated mitophagy of chondrocytes to alleviate osteoarthritis
Acta Pharmaceutica Sinica B|2024
25 cit.
7
The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants
Antiviral Research|2024
23 cit.
8
RepurposeDrugs: an interactive web-portal and predictive platform for repurposing mono- and combination therapies
Briefings in Bioinformatics|2024
20 cit.
9
ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts
Journal of Clinical Investigation|2024
19 cit.
10
Early transcriptional responses reveal cell type-specific vulnerability and neuroprotective mechanisms in the neonatal ischemic hippocampus
Acta Neuropathologica Communications|2025
5 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Mallar Bhattacharya
University of California, San Francisco
2
Kanyi Pu
Nanyang Technological University
3
Peter Smibert
10X Genomics (United States)
4
Wei Xu
Peking University
5
David G. Meckes
Tallahassee Orthopedic Clinic
6
Hao Xue
Shandong University
7
Kiril Bidzhekov
Ludwig-Maximilians-Universität München
8
Evan Z. Macosko
Broad Institute
9
Fei Chen
Broad Institute
10
Huaxi Yi
Ocean University of China

Papers

1
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease
Nature Neuroscience|2022
563 cit.
2
Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics
Nature Biomedical Engineering|2022
252 cit.
3
Early Alzheimer’s disease pathology in human cortex involves transient cell states
Cell|2023
208 cit.
4
Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
Nature|2023
198 cit.
5
Molecular radio afterglow probes for cancer radiodynamic theranostics
Nature Materials|2023
190 cit.
6
Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection
Nature Materials|2022
189 cit.
7
The molecular cytoarchitecture of the adult mouse brain
Nature|2023
183 cit.
8
Cell type-specific inference of differential expression in spatial transcriptomics
Nature Methods|2022
171 cit.
9
A Dual‐Locked Activatable Phototheranostic Probe for Biomarker‐Regulated Photodynamic and Photothermal Cancer Therapy
Angewandte Chemie International Edition|2022
169 cit.
10
Direct detection of RNA modifications and structure using single-molecule nanopore sequencing
Cell Genomics|2022
161 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Jan Lötvall
University of Gothenburg
2
Clotilde Théry
Inserm
3
David Lyden
Cornell University
4
Ewa Zuba‐Surma
Jagiellonian University
5
Raghu Kalluri
The University of Texas MD Anderson Cancer Center
6
Giovanni Camussi
University of Turin
7
Takahiro Ochiya
Unknown
8
Theresa L. Whiteside
UPMC Hillman Cancer Center
9
Sai Kiang Lim
Io Therapeutics (United States)
10
Xandra O. Breakefield
Harvard University

Papers

1
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Nature Cell Biology|2007
12.8k cit.
2
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Journal of Extracellular Vesicles|2018
11.2k cit.
3
Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
Current Protocols in Cell Biology|2006
5.8k cit.
4
Tumour exosome integrins determine organotropic metastasis
Nature|2015
5.1k cit.
5
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
Nature Cell Biology|2008
5k cit.
6
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Nature Medicine|2012
3.7k cit.
7
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
Proceedings of the National Academy of Sciences|2016
3.4k cit.
8
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
Nature|2005
3.2k cit.
9
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
Nature|2015
2.9k cit.
10
Rab27a and Rab27b control different steps of the exosome secretion pathway
Nature Cell Biology|2009
2.7k cit.

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