Leaderboards/enzyme function and inhibition

enzyme function and inhibition

Last updated June 11, 2026

Rising Stars

New and hot

Rising Stars Researchers

1
Yuqi Wang
Westlake University
99
2
Mehregan Babamohamadi
Kermanshah University of Medical Sciences
80
3
Cheng Sun
Nantong University
70
4
Nady Golestaneh
Georgetown University
60
5
Shuyan Zhou
Georgetown University
50
6
Sven M. Lange
Harvard University
40
7
Yogesh Kulathu
University of Dundee
30
8
Yuran Duan
Zhejiang Cancer Hospital
20
9
Daqian Xu
Harbin Medical University
10

Rising Stars Papers

1
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains
Nature Structural & Molecular Biology|2024
37 cit.
2
VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation
The EMBO Journal|2024
27 cit.
3
Sex-dependent regulation of retinal pigment epithelium and retinal function by Pgc-1α
Frontiers in Cellular Neuroscience|2024
10 cit.
4
Ablation of CD44 Attenuates Adipogenesis in White Adipocytes via the Tryptophan 5-Hydroxylase 2/5-Hydroxytryptamine Axis to Protect Mice from High-Fat Diet–Induced Obesity
American Journal Of Pathology|2024
8 cit.
5
Prenylation-dependent membrane localization of a deubiquitinating enzyme and its role in regulating G protein–mediated signaling in yeast
Journal of Biological Chemistry|2025
1 cit.

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

1
Katelyn D. Miller
The Wistar Institute
99
2
Yilong Zou
Westlake University
90
3
Alison Jaccard
Ludwig Cancer Research
90
4
Bolin Lian
Nantong University
80
5
Yu Du
Nanjing Normal University
70
6
Naoya Yamada
Jichi Medical University
60
7
Qianmin Ou
Sun Yat-sen University
40
8
Yuxuan Hu
Nanyang Technological University
30
9
Rizliya Visvanathan
Victorian Heart Hospital
10

Emerging Leaders Papers

1
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer
Nature Cancer|2023
110 cit.

All-Time Leaders

The canon

All-Time Leaders Researchers

1
Dennis J. Selkoe
Brigham and Women's Hospital
99
2
Yang Shi
Harvard University
90
3
Douglas Pat Cerretti
Unknown
80
4
Zhijian J. Chen
The University of Texas Southwestern Medical Center
70
5
Roberto Fernández‐Lafuente
Universidad Autónoma de Madrid
60
6
Paolo Sassone‐Corsi
University of California, Irvine
50
7
Mengqian Chen
University of South Carolina
50
8
Marc S. Sabatine
Brigham and Women's Hospital
40
9
Raymond F. Brown
Eli Lilly (United States)
30
10
Michael D. Miller
United States Military Academy
20

All-Time Leaders Papers

1
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
New England Journal of Medicine|2018
6.2k cit.
2
Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions
JAMA|2016
1.5k cit.
3
Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction
Cold Spring Harbor Perspectives in Medicine|2012
1k cit.
4
cGAS is essential for cellular senescence
Proceedings of the National Academy of Sciences|2017
966 cit.
5
Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk
Circulation|2019
930 cit.
6
Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors
Journal of Neuroscience|2011
653 cit.
7
Novozym 435: the “perfect” lipase immobilized biocatalyst?
Catalysis Science & Technology|2019
586 cit.
8
Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization
Chemical Society Reviews|2022
509 cit.
9
Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids
Annual Review of Microbiology|2018
439 cit.
10
Aggregation of Secreted Amyloid β-Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture
Journal of Biological Chemistry|1995
368 cit.

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