Leaderboards/CRISPR and Genetic Engineering

CRISPR and Genetic Engineering

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Martin Pacesa
École Polytechnique Fédérale de Lausanne
2
Ivan Aksamentov
SIB Swiss Institute of Bioinformatics
3
Eric Nguyen
Microsoft (United States)
4
Huawei Tong
Chinese Academy of Sciences
5
Luke W. Koblan
Howard Hughes Medical Institute
6
Meirui An
Broad Institute
7
Hafiza Arooj Razaq
Unknown
8
Samagya Banskota
Broad Institute
9
Han Altae-Tran
McGovern Institute for Brain Research
10
Joseph Nasser
Harvard University

Papers

1
Past, present, and future of CRISPR genome editing technologies
Cell|2024
499 cit.
2
Sequence modeling and design from molecular to genome scale with Evo
Science|2024
427 cit.
3
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
Nature Biotechnology|2024
236 cit.
4
Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylase
Nature Communications|2024
49 cit.
5
Publication in Nature Medicine (2025) [39 citations, W4406374689]
Nature Medicine|2025
39 cit.
6
High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer
Science|2025
23 cit.
7
Programmable G-to-Y base editing using engineered DNA glycosylase
Life Medicine|2024
1 cit.
8
Applications and properties of computationally designed <i>de novo</i> proteins
Structural Dynamics|2025
0 cit.
9
Publication in Digital Access to Scholarship at Harvard (DASH) (Harvard University) (2025) [W7133581441]
Digital Access to Scholarship at Harvard (DASH) (Harvard University)|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Omar O. Abudayyeh
Brigham and Women's Hospital
2
Jonathan S. Gootenberg
Brigham and Women's Hospital
3
Lucas B. Harrington
Mammoth Biosciences (United States)
4
Aviad Tsherniak
Broad Institute
5
Janice S. Chen
Mammoth Biosciences (United States)
6
Patrick D. Hsu
Innovative Genomics Institute
7
J Engreitz
Broad Institute
8
Maximilian Haeussler
University of California, Santa Cruz
9
Joseph Bondy‐Denomy
QB3
10
Fei Chen
Broad Institute

Papers

1
The UCSC Genome Browser database: 2025 update
Nucleic Acids Research|2024
579 cit.
2
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
Nature Biotechnology|2022
429 cit.
3
The UCSC Genome Browser database: 2024 update
Nucleic Acids Research|2023
358 cit.
4
Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
Nature Biotechnology|2022
206 cit.
5
Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
Nature|2023
198 cit.
6
Cell type-specific inference of differential expression in spatial transcriptomics
Nature Methods|2022
171 cit.
7
Compatibility rules of human enhancer and promoter sequences
Nature|2022
167 cit.
8
Rapid in silico directed evolution by a protein language model with EVOLVEpro
Science|2024
156 cit.
9
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
Nature Genetics|2022
144 cit.
10
Rapid detection of SARS-CoV-2 RNA in saliva via Cas13
Nature Biomedical Engineering|2022
139 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Feng Zhang
Broad Institute
2
Shinya Yamanaka
Kyoto University
3
Jennifer A. Doudna
QB3
4
Rudolf Jaenisch
Whitehead Institute for Biomedical Research
5
David R. Liu
New York Hospital Queens
6
Austin Smith
Wellcome/MRC Cambridge Stem Cell Institute
7
George M. Church
Harvard University Press
8
J. Keith Joung
Massachusetts General Hospital
9
Craig C. Mello
University of Massachusetts Chan Medical School
10
Gregory J. Hannon
University of Cambridge

Papers

1
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Cell|2006
26.5k cit.
2
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
Cell|2007
20.2k cit.
3
Multiplex Genome Engineering Using CRISPR/Cas Systems
Science|2013
15.7k cit.
4
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Nature|1998
15.3k cit.
5
Genome engineering using the CRISPR-Cas9 system
Nature Protocols|2013
11.7k cit.
6
RNA-Guided Human Genome Engineering via Cas9
Science|2013
9.4k cit.
7
Genomic sequencing.
Proceedings of the National Academy of Sciences|1984
8.2k cit.
8
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Science|2013
5.5k cit.
9
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Nature|2016
5.4k cit.
10
DNA targeting specificity of RNA-guided Cas9 nucleases
Nature Biotechnology|2013
4.9k cit.

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