Leaderboards/Biomedical Research and Pathophysiology

Biomedical Research and Pathophysiology

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Yuelong Yan
The University of Texas MD Anderson Cancer Center
2
Xiujin Shen
First Affiliated Hospital Zhejiang University
3
Yingyu Huang
The University of Texas at Dallas
4
Yuan-li Ai
Xiamen University
5
Jazlyn P. Borges
University of Toronto
6
Letian Yang
China University of Petroleum, East China
7
Olivier Devuyst
Cliniques Universitaires Saint-Luc
8
Nilesh Anand Devanand
Royal Adelaide Hospital
9
Huayu Fu
Sun Yat-sen University
10
Maria-Kyriaki Drekolia
Goethe University Frankfurt

Papers

1
Charge barriers in the kidney elimination of engineered nanoparticles
Proceedings of the National Academy of Sciences|2024
37 cit.
2
Publication in Journal of Controlled Release (2025) [26 citations, W4407771977]
Journal of Controlled Release|2025
26 cit.
3
Nanoparticle Transport in Proximal Tubules with Rhabdomyolysis‐Induced Necrosis
Angewandte Chemie International Edition|2024
10 cit.
4
GPR56: GPCR as a guardian against ferroptosis
Cell Metabolism|2024
4 cit.
5
Angiopoietin-like 4 exacerbates renal tubular epithelial cell pyroptosis in acute kidney injury via integrin β5/FAK signaling pathway
Kidney International|2025
4 cit.
6
pH-Responsive Self-Assembly of Renal-Clearable Nanoparticles in the Kidneys: One Assembly per Endosome
Journal of the American Chemical Society|2025
4 cit.
7
Dodging death
Nature Chemical Biology|2024
0 cit.
8
#2671 Renal tubular epithelial FFAR4 improves cellular senescence to alleviate interstitial fibrosis in CKD
Nephrology Dialysis Transplantation|2024
0 cit.
9
Publication in Angewandte Chemie (2024) [W4403531494]
Angewandte Chemie|2024
0 cit.
10
Publication in Biochemistry (2026) [W7138926623]
Biochemistry|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Xinyi Yang
Dali University
2
Hui Liang
Guangzhou Women and Children Medical Center
3
Nieraj Jain
Emory University
4
Alessandro Luciani
University of Zurich
5
Camilla Raiborg
Oslo University Hospital
6
Mohammadali Torbati
Tabriz University of Medical Sciences
7
Xinxin Ci
Jilin University
8
Monther Abu-Remaileh
Neurosciences Institute
9
Jun Wang
National Clinical Research Center for Digestive Diseases
10
Wenhui Yu
Northeast Agricultural University

Papers

1
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes
Nature|2022
140 cit.
2
LYC inhibits the AKT signaling pathway to activate autophagy and ameliorate TGFB-induced renal fibrosis
Autophagy|2023
122 cit.
3
Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system
Redox Biology|2022
99 cit.
4
Artificial intelligence chatbot performance in triage of ophthalmic conditions
Canadian Journal of Ophthalmology|2023
91 cit.
5
The Batten disease gene product CLN5 is the lysosomal bis(monoacylglycero)phosphate synthase
Science|2023
78 cit.
6
Golgi-IP, a tool for multimodal analysis of Golgi molecular content
Proceedings of the National Academy of Sciences|2023
67 cit.
7
TLR2/caspase-5/Panx1 pathway mediates necrosis-induced NLRP3 inflammasome activation in macrophages during acute kidney injury
Cell Death Discovery|2022
52 cit.
8
An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation
Science Advances|2023
46 cit.
9
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Nature Communications|2023
42 cit.
10
Daphnetin ameliorates PM2.5-induced airway inflammation by inhibiting NLRP3 inflammasome-mediated pyroptosis in CS-exposed mice
Biomedicine & Pharmacotherapy|2023
41 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Myles Wolf
Duke University
2
William A. Gahl
National Institute of Child Health
3
Stefan Somlo
Yale University
4
Prasad Devarajan
Cincinnati Children's Hospital Medical Center
5
Elena Levtchenko
Emma Kinderziekenhuis
6
Friedhelm Hildebrandt
Boston Children's Hospital
7
Mark Mitsnefes
University of Cincinnati
8
Kamyar Zahedi
New Mexico VA Health Care System
9
Qing Ma
University of North Carolina at Chapel Hill
10
Jing Zhou
Zunyi Medical University

Papers

1
Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery
The Lancet|2005
2.4k cit.
2
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
Nature Genetics|2003
2k cit.
3
FGF23 induces left ventricular hypertrophy
Journal of Clinical Investigation|2011
2k cit.
4
Identification of Neutrophil Gelatinase-Associated Lipocalin as a Novel Early Urinary Biomarker for Ischemic Renal Injury
Journal of the American Society of Nephrology|2003
1.7k cit.
5
Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis
New England Journal of Medicine|2008
1.7k cit.
6
<b> <i>PKD2</i> </b> , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
Science|1996
1.4k cit.
7
Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease
Kidney International|2011
1.2k cit.
8
Update on Mechanisms of Ischemic Acute Kidney Injury
Journal of the American Society of Nephrology|2006
1k cit.
9
Fibroblast Growth Factor-23 Mitigates Hyperphosphatemia but Accentuates Calcitriol Deficiency in Chronic Kidney Disease
Journal of the American Society of Nephrology|2005
914 cit.
10
Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease
Circulation|2009
827 cit.

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