Leaderboards/Barrier Structure and Function Studies

Barrier Structure and Function Studies

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Eszter Császár
HUN-REN Institute of Experimental Medicine
2
Mei Chenghan
Sichuan University
3
Weikang Luo
Central South University
4
Sophie Dithmer
Leibniz-Forschungsinstitut für Molekulare Pharmakologie
5
Iosif Pediaditakis
Forma Therapeutics (United States)
6
Sung-Hyun Yoon
Yonsei University
7
Galina Popova
Enzo Life Sciences (United States)
8
Evridiki Asimakidou
University of Cambridge
9
Shuang Qu
Army Medical University
10
Paolo d’Errico
University of Freiburg

Papers

1
Publication in International Journal of Molecular Sciences (2024) [97 citations, W4398222588]
International Journal of Molecular Sciences|2024
97 cit.
2
Publication in Pharmaceuticals (2024) [85 citations, W4396803213]
Pharmaceuticals|2024
85 cit.
3
Publication in ACS Nano (2024) [83 citations, W4403275728]
ACS Nano|2024
83 cit.
4
Publication in Annals of the New York Academy of Sciences (2025) [54 citations, W4407945334]
Annals of the New York Academy of Sciences|2025
54 cit.
5
Publication in Neural Regeneration Research (2024) [50 citations, W4398253428]
Neural Regeneration Research|2024
50 cit.
6
Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice
Nature Communications|2025
46 cit.
7
Publication in Advanced Functional Materials (2024) [19 citations, W4405558271]
Advanced Functional Materials|2024
19 cit.
8
Publication in Nature Metabolism (2025) [6 citations, W4416462393]
Nature Metabolism|2025
6 cit.
9
Publication in Advanced Functional Materials (2025) [5 citations, W4413996975]
Advanced Functional Materials|2025
5 cit.
10
Pharmacological modulation of the blood-brain barrier: Mechanisms, therapeutic strategies, and emerging technologies
Pharmacological Reviews|2026
2 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Ethan S. Lippmann
Vanderbilt University
2
Helena W. Morrison
University of Arizona
3
Nils Korte
Broad Institute
4
Anusha Mishra
Oregon Health & Science University
5
Zane Jaunmuktane
King's College London
6
Pablo Izquierdo
Unidades Centrales Científico-Técnicas
7
Chanawee Hirunpattarasilp
University Hospitals of Cleveland
8
Vasiliki Kyrargyri
Institut Pasteur
9
Quanwei He
Union Hospital
10
Orit Rozenblatt–Rosen
Broad Institute

Papers

1
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Nature Communications|2022
183 cit.
2
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia
Nature Neuroscience|2024
76 cit.
3
Noradrenaline released from locus coeruleus axons contracts cerebral capillary pericytes via <b>α</b> <sub>2</sub> adrenergic receptors
Journal of Cerebral Blood Flow & Metabolism|2023
50 cit.
4
Immune–vascular mural cell interactions: consequences for immune cell trafficking, cerebral blood flow, and the blood–brain barrier
Neurophotonics|2022
39 cit.
5
SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction
Brain|2022
38 cit.
6
Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids
Cell Reports|2024
30 cit.
7
Hyperoxia evokes pericyte-mediated capillary constriction
Journal of Cerebral Blood Flow & Metabolism|2022
27 cit.
8
Pathology of neurodegenerative disease for the general neurologist
Practical Neurology|2023
26 cit.
9
Prediction of Neurological Deterioration After Intracerebral Hemorrhage: The SIGNALS Score
Journal of the American Heart Association|2022
14 cit.
10
Nuclear receptor ligand screening in an iPSC-derived in vitro blood–brain barrier model identifies new contributors to leptin transport
Fluids and Barriers of the CNS|2022
14 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Berislav V. Zloković
University of Southern California
2
James M. Anderson
University of North Carolina at Chapel Hill
3
Jerrold R. Turner
Brigham and Women's Hospital
4
Christer Betsholtz
Uppsala University
5
Fritjof Helmchen
University of Zurich
6
Y. Thomas
University of New Mexico
7
Michael Fromm
Charité - Universitätsmedizin Berlin
8
Elisabetta Dejana
Uppsala University
9
Matthew Meyerson
Broad Institute
10
David Attwell
University College London

Papers

1
<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
Science|2004
9.4k cit.
2
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
Science|2005
5.8k cit.
3
The landscape of somatic copy-number alteration across human cancers
Nature|2010
4.1k cit.
4
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
The Journal of Cell Biology|2003
2.9k cit.
5
Pericytes regulate the blood–brain barrier
Nature|2010
2.8k cit.
6
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
Proceedings of the National Academy of Sciences|2001
2.6k cit.
7
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
Science|1997
2.2k cit.
8
Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
Neuron|2015
2.1k cit.
9
A molecular atlas of cell types and zonation in the brain vasculature
Nature|2018
2k cit.
10
Genomic analysis identifies association of <i>Fusobacterium</i> with colorectal carcinoma
Genome Research|2011
2k cit.

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