Leaderboards/Autophagy in Disease and Therapy

Autophagy in Disease and Therapy

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Daniel J. Klionsky
University of Michigan
2
Juan Ignacio Jiménez‐Loygorri
National Research Council
3
Ruei-Zeng Lin
Boston Children's Hospital
4
Ji-Man Park
University of Minnesota
5
Zhiya Deng
Nanfang Hospital
6
Claudio Bussi
Nanyang Technological University
7
Qingzhu Shi
Beijing Institute of Education
8
Yachun Han
Central South University
9
Brage Brakedal
Haukeland University Hospital
10
Jing Jin
University of Science and Technology of China

Papers

1
Mitophagy curtails cytosolic mtDNA-dependent activation of cGAS/STING inflammation during aging
Nature Communications|2024
289 cit.
2
Mitochondrial transfer mediates endothelial cell engraftment through mitophagy
Nature|2024
216 cit.
3
Urolithin A promotes p62-dependent lysophagy to prevent acute retinal neurodegeneration
Molecular Neurodegeneration|2024
24 cit.
4
Aging STINGs: mitophagy at the crossroads of neuroinflammation
Autophagy|2024
21 cit.
5
One size does not fit all: Lysosomes exist in biochemically and functionally distinct states
PLoS Biology|2024
17 cit.
6
Physiologic medium renders human iPSC-derived macrophages permissive for <i>M. tuberculosis</i> by rewiring organelle function and metabolism
mBio|2024
9 cit.
7
Recycling the recyclers: lysophagy emerges as a new pharmacological target for retinal degeneration
Autophagy|2024
7 cit.
8
Fast and quantitative mitophagy assessment by flow cytometry using the mito-QC reporter
Frontiers in Cell and Developmental Biology|2024
7 cit.
9
Defective chaperone-mediated autophagy in the retinal pigment epithelium of age-related macular degeneration patients
EMBO Molecular Medicine|2025
6 cit.
10
Publication in Trends in Cell Biology (2026) [W7140291096]
Trends in Cell Biology|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Chun-Kit Tong
Hong Kong Baptist University
2
Haoyan Chen
Shanghai Jiao Tong University
3
Muriel Mari
Aarhus University
4
Rushika M. Perera
University of California, San Francisco
5
Xiaoyang Su
Rutgers, The State University of New Jersey
6
Michael Lazarou
The University of Melbourne
7
Zhen Zou
Ministry of Education
8
Oliver Florey
Babraham Institute
9
Kailiang Zhou
Wenzhou Medical University
10
Viktor I. Korolchuk
Newcastle University

Papers

1
V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy
The Journal of Cell Biology|2022
171 cit.
2
Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
Molecular Cell|2023
113 cit.
3
Urea cycle activation triggered by host-microbiota maladaptation driving colorectal tumorigenesis
Cell Metabolism|2023
99 cit.
4
3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury
Theranostics|2023
95 cit.
5
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
The Journal of Cell Biology|2023
95 cit.
6
A guide to membrane atg8ylation and autophagy with reflections on immunity
The Journal of Cell Biology|2022
75 cit.
7
Autophagy promotes cell survival by maintaining NAD levels
Developmental Cell|2022
74 cit.
8
Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
Developmental Cell|2024
71 cit.
9
PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles
Journal of Nanobiotechnology|2022
64 cit.
10
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy
The EMBO Journal|2022
59 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Guido Kroemer
Institut Universitaire de France
2
Yoshinori Ohsumi
Tokyo Institute of Technology
3
Beth Levine
The University of Texas Southwestern Medical Center
4
Daniel J. Klionsky
University of Michigan
5
Noboru Mizushima
The University of Tokyo
6
Richard J. Youle
National Institutes of Health
7
Ana María Cuervo
Albert Einstein College of Medicine
8
Tamotsu Yoshimori
The University of Osaka
9
David C. Rubinsztein
UK Dementia Research Institute
10
Brent R. Stockwell
Columbia University

Papers

1
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell|2012
18.1k cit.
2
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell|2014
7.5k cit.
3
Autophagy in the Pathogenesis of Disease
Cell|2008
7k cit.
4
Autophagy fights disease through cellular self-digestion
Nature|2008
6.4k cit.
5
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy|2016
6k cit.
6
Methods in Mammalian Autophagy Research
Cell|2010
4.5k cit.
7
Molecular characterization of mitochondrial apoptosis-inducing factor
Nature|1999
4k cit.
8
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy|2012
4k cit.
9
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
The Journal of Cell Biology|2008
4k cit.
10
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Nature|2006
3.8k cit.

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