Leaderboards/Adipokines, Inflammation, and Metabolic Diseases

Adipokines, Inflammation, and Metabolic Diseases

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Nayili Mahemuti
Tianjin Medical University
2
Teresa Vilariño‐García
Hospital Universitario Virgen del Rocío
3
Arik Sheinenzon
Bar-Ilan University
4
Matthew L. Meizlish
Dana-Farber Cancer Institute
5
Andrew D. Hildreth
University of California, Los Angeles
6
Wenmin Xia
University of California San Diego
7
Fani‐Niki Varra
Democritus University of Thrace
8
Max C. Petersen
Washington University in St. Louis
9
Janane F. Rahbani
University of Chicago
10
Saredo Said
Novo Nordisk (Finland)

Papers

1
Role of Leptin in Obesity, Cardiovascular Disease, and Type 2 Diabetes
International Journal of Molecular Sciences|2024
155 cit.
2
Publication in Nature Metabolism (2024) [140 citations, W4391322596]
Nature Metabolism|2024
140 cit.
3
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation‑mediating treatment options (Review)
Molecular Medicine Reports|2024
139 cit.
4
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
Cell Metabolism|2024
124 cit.
5
Mechanosensing regulates tissue repair program in macrophages
Science Advances|2024
89 cit.
6
Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB
Cell Metabolism|2024
77 cit.
7
Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes
Diabetes|2024
14 cit.
8
Is Obesity a Modifiable Risk Factor in Multiple Sclerosis? Mechanistic Insights into Neuroinflammation and Oxidative Damage
Pathophysiology|2026
2 cit.
9
Mechanistic Insights into Antioxidant Interventions Targeting Obesity-Induced Oxidative Stress in the Pathogenesis and Complications of Type 2 Diabetes Mellitus
Current Issues in Molecular Biology|2025
1 cit.
10
Publication in Diabetes Obesity and Metabolism (2025) [W4408464556]
Diabetes Obesity and Metabolism|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Masako Nishizawa
National Institute of Infectious Diseases
2
Robert J. Glynn
Brigham and Women's Hospital
3
Kanakadurga Singer
University of Michigan
4
Niloufar Bagheri
University of Tehran
5
Helga Ellingsgaard
University of Copenhagen
6
Nathalie Pamir
Oregon Health & Science University
7
Jesper Grud Skat Madsen
Broad Institute
8
Ambar Grijalva
Columbia University
9
Saul J. Priceman
University of Southern California
10
Timothy E. O’Sullivan
University of California, Los Angeles

Papers

1
PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages
Journal for ImmunoTherapy of Cancer|2022
117 cit.
2
PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial
Nature Medicine|2024
116 cit.
3
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
Nature Communications|2023
102 cit.
4
Race-Dependent Association of High-Density Lipoprotein Cholesterol Levels With Incident Coronary Artery Disease
Journal of the American College of Cardiology|2022
51 cit.
5
Cold versus hot snare endoscopic mucosal resection for large (≥15 mm) flat non-pedunculated colorectal polyps: a randomised controlled trial
Gut|2024
45 cit.
6
MEF2C regulates NK cell effector functions through control of lipid metabolism
Nature Immunology|2024
38 cit.
7
Monocyte Trafficking and Polarization Contribute to Sex Differences in Meta-Inflammation
Frontiers in Endocrinology|2022
35 cit.
8
The transcription factor Fli1 restricts the formation of memory precursor NK cells during viral infection
Nature Immunology|2022
32 cit.
9
Adipose cDC1s contribute to obesity-associated inflammation through STING-dependent IL-12 production
Nature Metabolism|2023
30 cit.
10
Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery
Nature Biomedical Engineering|2025
30 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Bruce M. Spiegelman
Dana-Farber Cancer Institute
2
Yūji Matsuzawa
Sumitomo Hospital
3
Takashi Kadowaki
Toranomon Hospital
4
Philipp E. Scherer
The University of Texas Southwestern Medical Center
5
Anthony W. Ferrante
Columbia University
6
Iichiro Shimomura
The University of Osaka
7
Stephen O’Rahilly
Wellcome/MRC Institute of Metabolic Science
8
Jeffrey S. Flier
Harvard University
9
Hong Chen
Ningxia Medical University
10
Jeffrey M. Friedman
Rockefeller University

Papers

1
Positional cloning of the mouse obese gene and its human homologue
Nature|1994
13.4k cit.
2
Obesity is associated with macrophage accumulation in adipose tissue
Journal of Clinical Investigation|2003
8.6k cit.
3
Obesity is associated with macrophage accumulation in adipose tissue
Journal of Clinical Investigation|2003
8.3k cit.
4
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
Science|1993
7.5k cit.
5
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Journal of Clinical Investigation|2003
5.8k cit.
6
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Journal of Clinical Investigation|2003
5.7k cit.
7
Increased oxidative stress in obesity and its impact on metabolic syndrome
Journal of Clinical Investigation|2004
5.3k cit.
8
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
Nature Medicine|2001
4.9k cit.
9
Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity
Biochemical and Biophysical Research Communications|1999
4.9k cit.
10
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Nature|2012
4.7k cit.

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