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Hien Nguyen Minh

VNU University of Science

Publishes on AI in cancer detection, Gene expression and cancer classification, Bioinformatics and Genomic Networks. 2 papers and 1 citations.

2Publications
1Total Citations

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Top publicationsby citations

Multi-Omics Biomarker Discovery with Explainable Artificial Intelligence: A Case Study in Glioblastoma
Hoang Le, Hien Nguyen Minh, Ha Tang Vinh et al.|Unknown|2024
Cited by 1

Accurately predicting the molecular subtype of cancer is crucial for personalized diagnosis and treatment. Furthermore, finding reliable biomarkers is essential for achieving personalized medicine and improving patient outcomes overall. This paper presents a novel approach for multi-omics biomarker discovery in Glioblastoma using explainable artificial intelligence. The proposed method integrated data from the TCGA cohort and MOGONET's deep learning model for subtyping problems and then used the Integrated Gradients algorithm to discover important features in the multi-omics data. The identified biomarkers were subsequently validated through two approaches: first, by comparing them with established ground truth data from reference databases, and second, performance evaluation using classical machine learning models.