Si M. Pham, Robert L. Kormos, Brack Hattler et al.|Journal of Thoracic and Cardiovascular Surgery|1996
Cited by 160Open Access
University of Florida
Publishes on Congenital Heart Disease Studies, Transplantation: Methods and Outcomes, Mechanical Circulatory Support Devices. 89 papers and 2.7k citations.
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In concert with the adult trial of FK 506 begun in October 1989 at Presbyterian University Hospital, a similar trial to investigate the use of FK 506 as both primary and rescue immunotherapy was initiated in the pediatric population at Children’s Hospital of Pittsburgh. In a prospective clinical trial 19 pediatric patients have undergone orthotopic cardiac transplantation with FK 506 and low-dose steroids as primary immunosuppression. Encouraging results have also been obtained in four children with refractory cardiac rejection who have undergone rescue therapy with FK 506.